Copy Number Variation Clinical Trial
Copy Number Variation in Prenatal Diagnosis
An observed study is aim to map the CNVs distribution in human genome of Chinese prenatal
Setting: Prenatal diagnosis center of Taizhou City, Zhejiang Province Patient: total cases of pregnant women needed prenatal genetic diagnosing Methods: karyotype was performed with combined of molecular and cytogenic protocol. Subgroup: molecular karyotyping performed by genomic Chip (CMA) or NGS, the latter including cnv-seq and NIPT.
Main outcome: comparison of CNVs distributions in subgroups. Second outcome: comparison of CNVs distributions in demographic dates.
|Start date||December 1, 2016|
|Completion date||December 30, 2020|