Assessment Of Different Scores In Predicting Outcome In AECOPD Patients In Emergency Department

Chronic Obstructive Pulmonary Disease Clinical Trial

Official title:

Assessment Of Different Scores In Predicting Outcome In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Patients In Emergency Department

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05793697
• Other study ID #: different scores in AECOPD
• Status: Not yet recruiting
• Start date: May 3, 2023
• Est. completion date: December 3, 2024

Study information

• Verified date: March 2023
• Source: Assiut University
• Contact: mohamed mo saleh, bachelor
• Phone: 01128534859
• Email: drmohamed33333[@]gmail.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

evaluate the value of different scores in predicting hospital mortality and Need for MV In patients presented to ED with AECOPD.

Description:

Chronic obstructive pulmonary disease (COPD) is one of the top three causes of death worldwide, and 90% of deaths occur in low- and middle-income countries.

Acute exacerbation of chronic obstructive pulmonary disease(AECOPD) is defined as an acute change in patient's dyspnea, cough, or sputum beyond normal variability that is sufficient to warrant a change in therapy. AECOPD has a negative effect on the quality of life, admission and readmission rates, and disease progression.

For these reasons, appropriate management of acute exacerbations is recommended by national and international organizations.

Identifying high-risk dying patients on hospital admission helps in triaging them to the required level of care.

The use of early warning scores in follow-up is recommended for the early detection of critically ill patients and the prediction of clinical deterioration. CURB65, BAP65, qSOFA , DECAF and NEWS, which mainly involve mental status, respiratory rate, oxygen saturations, pulse, blood pressure, age, BUN level, etc., can be used to predict AECOPD-associated mortality in ED given the simple structure and data availability.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 139
• Est. completion date: December 3, 2024
• Est. primary completion date: January 3, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• All patient presented to ED with acute exacerbation of COPD.

Exclusion Criteria:

• Patient presented with acute insult affecting other system.

• Patient transferred to other centers.

• Inadequate data.

Related Conditions & MeSH terms

• Chronic Obstructive Pulmonary Disease
• Emergencies
• Lung Diseases
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (1)

Redfern OC, Smith GB, Prytherch DR, Meredith P, Inada-Kim M, Schmidt PE. A Comparison of the Quick Sequential (Sepsis-Related) Organ Failure Assessment Score and the National Early Warning Score in Non-ICU Patients With/Without Infection. Crit Care Med. 2018 Dec;46(12):1923-1933. doi: 10.1097/CCM.0000000000003359. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Evaluate the value of different scores in predicting hospital mortality	Assessment Of Different Scores In Predicting Outcome In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Patients In Emergency Department as DECAF(dyspnea grade V according to eMRCD,esinopenia<0.05x10*9/L,consolidation,acidemia<7.30,atrial fibrillation); 1=mild,2_3=moderate,4_5=severe can be used to predict AECOPD-associated mortality in ED given the simple structure and data availability.	one year
Secondary	Value of these scores in predicting need for MV.	Value of these scores in predicting need for MV in AECOPD patient in ER	one year