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Clinical Trial Summary

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in older Americans. COPD increases in frequency with age, and older adults with COPD often have significant unmet geriatrics-palliative care needs that results in reduced quality of life, high healthcare utilization, and care at the end of life that does not align with the values and wishes of patients and their care partners. Older adults with COPD could benefit from proactive geriatrics-palliative care before the end of life. However, no geriatrics-palliative care interventions have been systematically developed and tested in community-dwelling older adults with COPD and their care partners. As the number of older adults with COPD increases to levels unmatched by current palliative care workforce trends, innovative strategies are desperately needed to improve the delivery of geriatrics-palliative care in COPD before the end of life. Project EPIC (Early Palliative Care In COPD) is a multiphase study to refine and pilot test the ENABLE-COPD early palliative care intervention in older adults with COPD and their care partners. ENABLE (Educate, Nurture, Advise Before Life Ends) is an early palliative care intervention that improves quality of life and mood for patients with advanced cancer and has underwent decades of iterative refinement and rigorous randomized controlled trial testing. In the intervention, palliative care-trained nurse coaches deliver the Charting Your Course Curriculum over the phone to patients (six sessions) and their care partners (four sessions), with activities and monthly telephone follow-up following a manualized curriculum. We conducted a formative evaluation in a diverse and multidisciplinary group of stakeholders to refine ENABLE for patients with COPD and pilot tested the potential feasibility of the refined intervention, ENABLE-COPD, in patients and their care partners. The current study summatively evaluates ENABLE-COPD through a hybrid type-1 effectiveness-implementation pilot randomized controlled trial in dyads of community-dwelling older adults with moderate to very severe COPD and their care partners randomized to usual COPD care (control) versus usual COPD care + ENABLE-COPD (intervention). The primary outcomes are trial and intervention feasibility and acceptability. Secondary geriatrics-palliative care outcomes include Life-Space mobility, quality of life, cognitive impairment, functional status, healthcare utilization, palliative care uptake, and care partner burden.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05040386
Study type Interventional
Source University of Alabama at Birmingham
Contact Jazmine Coffee-Dunning
Phone (205) 996-3679
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date January 1, 2022
Completion date May 2024

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