Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Time point difference of AT from 1st week to 6th week |
Use cardiopulmonary exercise test (CPET) to get the change of time point difference of AT from 1st week(intervention starts) to 6th week(intervention ends) |
From 1st week to 6th week |
|
Primary |
Time point difference of AT from 1st week to 12th week |
Use cardiopulmonary exercise test (CPET) to get the change of time point difference of AT from 1st week(intervention starts) to 12th week(follow up ends) |
From 1st week to 12th week |
|
Primary |
Time point difference of AT from 6th week to 12th week |
Use cardiopulmonary exercise test (CPET) to get the change of time point of AT from 6th week(intervention ends) to 12th week(follow up ends) |
From 6th week to 12th week |
|
Primary |
Change of maximal exercise work from 1st week to 6th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of the pateint's total work (watt) from 1st week(intervention starts) to 6th week(intervention ends) |
From 1st week to 6th week |
|
Primary |
Change of maximal exercise work from 1st week to 12th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of the pateint's total work (watt) from 1st week(intervention starts) to to 12th week(follow up ends) |
From 1st week to 12th week |
|
Primary |
Change of maximal exercise work from 6th week to 12th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of the pateint's total work (watt) from 6th week(intervention ends) to 12th week(follow up ends) |
From 6th week to 12th week |
|
Primary |
Change of VO2max from 1st week to 6th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of VO2max (mL/min/kg) from 1st week(intervention starts) to 6th week(intervention ends) |
From 1st week to 6th week |
|
Primary |
Change of VO2max from 1st week to 12th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of VO2max (mL/min/kg) from 1st week(intervention starts) to 12th week(follow up ends) |
From 1st week to 12th week |
|
Primary |
Change of VO2max from 6th week to 12th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of VO2max (mL/min/kg) from 6th week(intervention ends) to 12th week(follow up ends) |
From 6th week to 12th week |
|
Primary |
Change of VE/VCO2 from 1st week to 6th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of VE/VCO2 from 1st week(intervention starts) to 6th week(intervention ends) |
From 1st week to 6th week |
|
Primary |
Change of VE/VCO2 from 1st week to 12th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of VE/VCO2 from 1st week(intervention starts) to 12th week(follow up ends) |
From 1st week to 12th week |
|
Primary |
Change of VE/VCO2 from 6th week to 12th week |
Use cardiopulmonary exercise test (CPET) to get the change of values of VE/VCO2 from 6th week(intervention ends) to 12th week(follow up ends) |
From 6th week to 12th week |
|
Primary |
Change of muscle strength from 1st week to 6th week |
Use dynamometer to measure the changes of muscle strength(kg) from 1st week(intervention starts) to 6th week(intervention ends), including bilateral handgrip, elbow flexors (biceps) and knee extensors (quadriceps) for 3 times separately.The patient need to increase the strength to the highest level in 6 seconds and rest for 30 seconds.The highest value will be divided by the patient's body weight (kg/kg) |
From 1st week to 6th week |
|
Primary |
Change of muscle strength from 1st week to 12th week |
Use dynamometer to measure the changes of muscle strength(kg) from 1st week(intervention starts) to 12th week(follow up ends), including bilateral handgrip, elbow flexors (biceps) and knee extensors (quadriceps) for 3 times separately.The patient need to increase the strength to the highest level in 6 seconds and rest for 30 seconds.The highest value will be divided by the patient's body weight (kg/kg) |
From 1st week to 12th week |
|
Primary |
Change of muscle strength from 6th week to 12th week |
Use dynamometer to measure the changes of muscle strength(kg) from 6th week(intervention ends) to 12th week(follow up ends), including bilateral handgrip, elbow flexors (biceps) and knee extensors (quadriceps) for 3 times separately.The patient need to increase the strength to the highest level in 6 seconds and rest for 30 seconds.The highest value will be divided by the patient's body weight (kg/kg) |
From 6th week to 12th week |
|
Primary |
Change of 6-minute walk test from 1st week to 6th week |
Measure the change of 6-minute walk test from 1st(intervention starts) week to 6th week(intervention ends).The patient walks in his/her own pace, as far as he/she can in 6 minutes at the 20-meter long straight path and the we will record the distance in meter.Stop when time's up or patient develops clinical symptoms. |
From 1st week to 6th week |
|
Primary |
Change of 6-minute walk test from 1st week to 12th week |
Measure the change of 6-minute walk test from 1st(intervention starts) week to 12th week(follow up ends).The patient walks in his/her own pace, as far as he/she can in 6 minutes at the 20-meter long straight path and the we will record the distance in meter.Stop when time's up or patient develops clinical symptoms. |
From 1st week to 12th week |
|
Primary |
Change of 6-minute walk test from 6th week to 12th week |
Measure the change of 6-minute walk test from 6th(intervention ends) week to 12th week(follow up ends).The patient walks in his/her own pace, as far as he/she can in 6 minutes at the 20-meter long straight path and the we will record the distance in meter.Stop when time's up or patient develops clinical symptoms. |
From 6th week to 12th week |
|
Primary |
Attendance rate in video group or booklet group |
If the patient completes 70% or more of the intervention program by being analyzed from the record of RPE form, he/she will be recognize as being completed the intervention.Finally, we will count the number of the patients who completed the intervention to be divided by the number of totally patients in video/booklet group at 6th week. |
From 1st week to 6th week |
|
Secondary |
FEV1 |
Use spirometry to measure the values of FEV1 (%) for 3 times.The highest result will be recored. |
Baseline, 6 weeks later, and 12 weeks later |
|
Secondary |
FEV1/FVC |
Use spirometry to measure the values of FEV1/FVC for 3 times.The highest result will be recored. |
Baseline, 6 weeks later, and 12 weeks later |
|
Secondary |
Modified Medical Research Council (mMRC) |
Level of Modified Medical Research Council (mMRC) |
Baseline, 6 weeks later, and 12 weeks later |
|
Secondary |
COPD Assessment Test (CAT) |
Total score of COPD Assessment Test (CAT) |
Baseline, 6 weeks later, and 12 weeks later |
|
Secondary |
EuroQol-5 Dimensions-5 Levels (EQ-5D-5L) |
Score of EuroQol-5 Dimensions-5 Levels (EQ-5D-5L) |
Baseline, 6 weeks later, and 12 weeks later |
|
Secondary |
Clinical COPD Questionnaires (CCQ) |
Score of Clinical COPD Questionnaires (CCQ) |
Baseline, 6 weeks later, and 12 weeks later |
|