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COPD and Inflammatory Mediators

COPD Clinical Trial

Official title:
Comparison of Exercise Training

Clinical Trial Summary

Chronic obstructive pulmonary disease (COPD) is widely spread all over the world. It is predicted to be the third leading cause of death by 2020.

Clinical Trial Description

COPD is a common, preventable treatable disease that is characterized by an airflow limitation which is not fully reversible.Not only the long-term exposition to noxious particles and gases contributes to the development of COPD, but also many others factors such as genetics and cigarette smoking. Cigarettes are harmful and contribute to different extra pulmonary disorders. Although COPD affects lungs some extrapulmonary manifestations are prescribed such as muscle dysfunction, abnormal respiratory muscles and systemic inflammation. Indeed, the systemic inflammation[6, 8] is considered as a key process in the pathogenesis of COPD. It involves different cells and molecules; high levels of circulating of white blood cells, increased plasma c-reactive proteins (CRP), interleukin 6 (Il6) have been reported in.those patients.Likewise, systemic inflammation could worsen the comorbidities (cardiovascular, osteoporosis..) and may lead to the exercise limitation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04271124
Study type Interventional
Source Faculty of Medicine, Sousse
Contact Amal Acheche, PhD
Phone 00216 55028619
Email acheche_amal@hotmail.com
Status Recruiting
Phase N/A
Start date May 2020
Completion date July 2020
View Details
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