COPD Clinical Trial
Official title:
The BRAVE Study: Borg Score Outcomes in Respiratory Compromised Acute Exacerbating COPD Patients Receiving Treatment Via Vibrating Mesh Nebuliser Versus Jet Nebuliser in the Emergency Department
The purpose of this study is to compare clinical outcomes in patients with acute COPD treated
with a vibrating mesh nebuliser (VMN) versus a current standard jet nebuliser (JN), in the
Emergency Department (ED).
Participants will be those who meet the inclusion criteria and have a primary diagnosis of
COPD, and consent to take part in the study. Operators will be clinical staff including
doctors and nurses who will be trained in the use of the nebulisers.
Delivery of current treatment standards utilising a VMN compared to a JN will improve symptom
scores in patients attending ED with COPD exacerbations.
This study is a prospective, single-centre, open, randomised study to improve management of acute COPD exacerbation within the Emergency Department. Adults with severe COPD are randomised into 2 groups: vibrating mesh nebuliser or standard jet nebuliser treatment. Salbutamol (5mg) and Ipratropium (0.5mg) will be administered via Aerogen Ultra via valved mask or a standard jet nebuliser via open face mask/. Two further doses of salbutamol to be delivered. ;
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