The Copmparison of Accuracy of PtcCO2 and in PetCO2 in COPD Patients

COPD Clinical Trial

Official title:

The Copmparison of Accuracy of PtcCO2 and in PetCO2 in COPD Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04051931
• Other study ID #: 2019-27
• Status: Recruiting
• Start date: August 10, 2019
• Est. completion date: June 1, 2020

Study information

• Verified date: October 2019
• Source: The First Affiliated Hospital of Guangzhou Medical University
• Contact: Shanshan Zha, master
• Phone: 15013023031
• Email: zhass2011[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The pathophysiological characteristics of COPD is irreversible airflow restriction which may influence the gas exchange and cause the abnormal PaO2 and PaCO2. Assessment of the partial arterial pressure of carbon dioxide (PaCO2 ) is the 'gold standard' for the evaluation of the adequacy of alveolar ventilation.Method used mostly nowadays : arterial puncture which is accurate but is invasive 、painful、 non-dynamic and there is risk of infection and tissue、nerve damage. Noninvasive measurement methods (Most commonly used)： end-tidal CO2（ ETCO2）、 transcutaneous CO2(TcCO2). They all can monitor the PaCO2 dynamically、 noninvasively, but is existence of controversy of the accuracy. So the investigators want to compare the accuracy of these two noninvasive methods for assessment of PaCO2.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: June 1, 2020
• Est. primary completion date: June 1, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 100 Years

Eligibility

Inclusion Criteria:

• COPD patients

Exclusion Criteria:

• hemodynamics is unstable;

• any other lung disease despite COPD;

• other diseases influencing experiments: Cognitive impairment disease? mouth and nose trauma.

Related Conditions & MeSH terms

• COPD

Locations

Country	Name	City	State
China	The First Affiliated Hospital of Guangzhou Medical University	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
The First Affiliated Hospital of Guangzhou Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	concordance between the values of PetCO2 and PaCO2 measured at the same time	concordance between the values of PetCO2 and PaCO2 measured at the same time	1 hour
Primary	concordance between the values of PtcO2 and PaCO2 measured at the same time	concordance between the values of PtcO2 and PaCO2 measured at the same time	1 hour