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Exercise Training and Inflammatory Mediators in COPD

COPD Clinical Trial

Official title:
Effect of Exercise Training on Inflammatory Mediators in COPD

Clinical Trial Summary

Chronic obstructive pulmonary disease (COPD) is widely spread all over the world. It is predicted to be the third leading cause of death by 2020[1]. COPD is a common, preventable treatable disease that is characterized by an airflow limitation which is not fully reversable[2].

Clinical Trial Description

Chronic obstructive pulmonary disease (COPD) is widely spread all over the world. It is predicted to be the third leading cause of death by 2020. COPD is a common, preventable treatable disease that is characterized by an airflow limitation which is not fully reversable.Not only the long-term exposition to noxious particles and gases contributes to the development of COPD, but also so many others factors such as genetics and cigarette smoking. It has been shown that cigarettes are harmful and contributed to different extra pulmonary disorders. Indeed, it induced a systemic inflammation that was considered as a key process in the pathogenesis of COPD and triggered the activation of inflammatory cells and an abnormal increase of circulating cytokines such as CRP, interleukin (IL6), IL8, tumor necrosis factor alpha (TNF alpha) and leptin. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03853174
Study type Interventional
Source Faculty of Medicine, Sousse
Contact
Status Completed
Phase N/A
Start date January 1, 2019
Completion date April 27, 2019
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