Clinical Outcomes in Patients Referred to Pulmonary Rehabilitation

Chronic Obstructive Pulmonary Disease Clinical Trial

Official title:

Longitudinal Study of Clinical Outcomes in Patients Referred to Pulmonary Rehabilitation

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03591263
• Other study ID #: 201805017RINB
• Status: Recruiting
• Start date: June 25, 2018
• Est. completion date: June 25, 2024

Study information

• Verified date: April 2023
• Source: National Taiwan University Hospital
• Contact: Ping-Lun Hsieh
• Phone: +886-905925933
• Email: 107673[@]ntuh.gov.tw
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Chronic obstructive pulmonary disease is a chronic inflammatory lung disease that causes obstructed airflow from the lung, characterized by chronic cough, dyspnea, and sputum production, which often misunderstood as aging or catching a cold. These symptoms may be progressive over time. To provide better disease management and early detecting, pulmonary rehabilitation is now considered a fundamental component of the integrated disease management of this population. However, few studies have evaluated the beneficial outcomes in patients referred to pulmonary rehabilitation. Therefore, the purpose of this study is to investigate the clinical outcomes in patients referred to pulmonary rehabilitation in National Taiwan University Hospital.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1000
• Est. completion date: June 25, 2024
• Est. primary completion date: June 25, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion criteria:

1. age > 20 years old

2. patients with chronic respiratory disease diagnosed by physician that referred to pulmonary rehabilitation in National Taiwan University Hospital including, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, bronchiectasis

3. can cooperate with pulmonary rehabilitation clinic

Exclusion criteria:

1. angina, acute myocardial infarction in the previous one month

2. pregnancy

Related Conditions & MeSH terms

• Chronic Obstructive Pulmonary Disease
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Intervention

Other:
• Pulmonary rehabilitation
Pulmonary rehabilitation as routine care includes, airway clearance techniques, breathing exercise, and physical training instruction

Locations

Country	Name	City	State
Taiwan	Physical Therapy Center at National Taiwan University Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Functional exercise capacity using the six-minute walk test	The six-minute walk test is commonly performed to evaluate functional exercise capacity. The six-minute walk test was performed according to the guidelines, and the distance walked in the test presented as functional exercise capacity.	The six-minute walk test needs six minute to complete the test
Primary	Muscle strength: hand grip	Hand grip strength is performed by using hand dynamometer	Hand grip of both hands need about three minutes to complete
Primary	Lung hygiene	Lung hygiene is evaluated by the frequency of acute exacerbation	Lung hygiene is evaluated as the frequency of acute exacerbation in the the past one year
Primary	Home-based physical activity	All subjects were encouraged to increase their daily physical activity and recorded the amount of physical activity on patient-self-record training log.	Record the home-based physical activities everyday that the subjects have in the past one week that lasting for one year.
Primary	Muscle strength: leg press	Maximum leg press is performed by using seated leg press machine	Maximum leg press measurement needs about four minutes to complete
Primary	Heart rate	Heart rate is measured at rest, during hospital-based physical training.	Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously
Primary	Blood pressure	systolic and diastolic pressure are measured at rest, during hospital-based physical training.	Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously
Primary	Perceived dyspnea	Rating of perceived dyspnea is measured by using Borg scale at rest, during hospital-based physical training, and home-based physical activity. The most widely used tool is the "Borg scale", with rating ranges from 0 (nothing at all) to 10 (extremely dyspnea).	It takes less than one minute to evaluate perceived dyspnea.
Primary	Oxygen saturation	Oxygen saturation is continuously monitored by pulse oximetry throughout Hospital-based physical training.	Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously