Associations Between Air Pollutants Exposures and Respiratory System Study

Chronic Obstructive Pulmonary Disease Clinical Trial

Official title:

Associations Between Air Pollutants Exposures and Respiratory System Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02964117
• Other study ID #: Apers Study
• Status: Completed
• Phase: N/A
• First received: October 31, 2016
• Last updated: November 10, 2016
• Start date: November 2014
• Est. completion date: January 2016

Study information

• Verified date: November 2016
• Source: Peking University Third Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: Beijing Municipal Science and Technology Commission
• Study type: Observational

Clinical Trial Summary

Epidemiological investigations has suggested exposure to air pollution linked with respiratory disease, especially chronic obstructive pulmonary disease. However, the potential mechanisms of adverse effects remains scare. The present study will assess the association between air pollutants and respiratory related parameters to elucidate possible mechanisms.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 106
• Est. completion date: January 2016
• Est. primary completion date: January 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 23 Years to 82 Years

Eligibility

Inclusion Criteria:

• Long-term residents, aged >23 and <82 years

Exclusion Criteria:

• Severe cardiopulmonary diseases, active inflammatory diseases, cancer

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Chronic Obstructive Pulmonary Disease
• Lung Diseases
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Peking University Third Hospital	Peking University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Lung Function indices were performed in peking university third hospital	Lung Function indices including FEV1(ml), FVC(ml),the ratio of FEV1/FVC et, al.. When we perform data analysis,these parameters will be expressed as the percentage of the predicted values based on the subject-specific sex, age,height and weight.	Repeated-measure study was conducted from November,2014 to January,2016,lung function was measured by every four months	No
Secondary	Inflammation related biomarkers were measured by flow cytometry	Inflammation related factors including IL,TNFa et, al. all biomarkers units are pg/ml.	Repeated-measure study was conducted from November,2014 to January,2016,biomarkers were measured by every four months	No