Effects of Vibration Training on Exercise Capacity in COPD-patients

Chronic Obstructive Pulmonary Disease Clinical Trial

Official title:

Effects of Vibration Training During a Three-week Rehabilitation on Exercise Capacity in Chronic Obstructive Pulmonary Disease (COPD) III/IV-Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01380639
• Other study ID #: BGL-Ga-6MGT-0810
• Status: Completed
• Phase: N/A
• Start date: September 2010
• Est. completion date: April 2011

Study information

• Verified date: April 2019
• Source: Klinikum Berchtesgadener Land der Schön-Kliniken
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to investigate the exercise capacity in COPD-patients performing a vibration training additional to a standard three-week rehabilitation program in comparison to patients performing merely a rehabilitation program.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 72
• Est. completion date: April 2011
• Est. primary completion date: April 2011
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Chronic obstructive pulmonary disease III/IV

Exclusion Criteria:

• Severe exacerbations in the last 4 weeks prior to begin of study (definition of exacerbation: symptoms on more than 3 days with a relevant change in drug therapy (cortisone, antibiotics))

• Severe disease other than COPD, that could influence the results of the study

• Abuse of alcohol or drugs

• Simultaneously participation in another study

• Tachypnea (>30/min)

• Severe exacerbation during rehabilitation

• Cardiac insufficiency (NYHA IV)

• Myocardial infarction during the last 6 weeks

• Mental-health problem

• Pregnancy

• Known HIV-infection

• Slipped disk

• Acute discopathy

• Acute thrombosis

• Implants in trained regions of the body (lower extremities)

• Acute inflammation of the locomotor system, active arthrosis or rheumatoid arthritis

• Acute tendinopathy in trained regions of the body

• Acute hernia

• Fresh fractures, wounds or scars in trained regions of the body

• Gallstones or stones in the urinary tract collection system

Related Conditions & MeSH terms

• Chronic Obstructive Pulmonary Disease
• Lung Diseases
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Intervention

Other:
• whole body vibration training
performing squats for 3x3 minutes while using vibration platform three times a week

Locations

Country	Name	City	State
Germany	Schön Klinikum Berchtesgadener Land	Schönau am Königssee

Sponsors (1)

Lead Sponsor	Collaborator
Klinikum Berchtesgadener Land der Schön-Kliniken

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	6-Minute-Walking-Distance	Change in 6-minute-walking-distance from baseline to day 19	day 1, day 19
Secondary	Body Composition	Change in body composition from baseline to day 19	day 1 and 19
Secondary	Isometric Maximum Handgrip Force	change in isometric max. handgrip force from baseline to day 19	day 1, day 19
Secondary	BODE-Score	Change in Bode-Score from baseline to day 19	day 1, day 19
Secondary	Lung Function		day 1
Secondary	Arterial Blood Gas		day 1
Secondary	Brain Natruretic Peptide (BNP)	change in BNP from baseline to day 19	day 1, day 19