Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in Chronic Obstructive Pulmonary Disease
Pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen
saturation in patients with chronic obstructive pulmonary disease (COPD) at rest. Although
PLB is a strategy that potentially reduces expiratory flow limitation, there are only few
studies addressing its effects on exercise.
This study aimed to assess the ability of PLB to change the breathing pattern, degree of
dynamic hyperinflation (DH) and arterial oxygenation in COPD patients during exercise.
Exercise tolerance was evaluated by endurance time and respiratory mechanics was evaluated
by forced oscillation technique.
Status | Completed |
Enrollment | 40 |
Est. completion date | October 2009 |
Est. primary completion date | October 2009 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 40 Years and older |
Eligibility |
Inclusion Criteria: - Clinical diagnosis of chronic obstructive pulmonary disease (COPD) - Regular treatment at Clementino Fraga Filho University Hospital (UFRJ) Exclusion Criteria: - Exacerbation in the preceding 4 weeks - SpO2<85% at peak exercise - Other diseases that may contribute to dyspnea and exercise intolerance |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Brazil | Clementino Fraga Filho University Hospital | Rio de Janeiro |
Lead Sponsor | Collaborator |
---|---|
Universidade Federal do Rio de Janeiro |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Endurance time | within the first 01 hour | No | |
Secondary | inspiratory capacity | within the first 01 hour | No | |
Secondary | oxygen saturation | within the first 01 hour | No | |
Secondary | dyspnea | within the first 01 hour | No | |
Secondary | forced oscillation variables | within the first 01 hour | No |
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