Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Respiratory Muscle Stretching in Patients With Chronic Obstructive Pulmonary Disease Submitted a Pulmonary Rehabilitation Program
Objective: The investigators studied the effects of respiratory muscle stretching in an 8-week pulmonary rehabilitation program. Methods: This was a simple-blind parallel controlled trial, conducted an out-patient clinic. Twenty six patients with COPD (mean age 68 ± 6 y, percent of predicted FEV1 47 ± 16) were randomized to either respiratory muscle stretching group plus exercise training (RMS), and exercise training group (Sham), in an 8-week exercise program that had 3 sessions per week. The investigators measured inspiratory and expiratory muscle strength (by maximal inspiratory and expiratory pressure - PIM and PEM), exercise capacity (by 6-minute walk distance), dyspnea and quality of life.
Status | Completed |
Enrollment | 26 |
Est. completion date | December 2008 |
Est. primary completion date | December 2006 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 40 Years to 75 Years |
Eligibility |
Inclusion Criteria: - Subjects between 40 and 75 years of age referred by a physician to the Pulmonary Rehabilitation Program - With a clinical and spirometric diagnosis of moderate to severe COPD according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD), in a stable condition (without exacerbations or infections for at least a month) - Former smokers Exclusion Criteria: - Patients with a known history of asthma, or severe and/or unstable heart disease - Any other pathological condition that could impair their physical activities |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Brazil | Faculdade Evangelica do Paraná | Curitiba | Paraná |
Lead Sponsor | Collaborator |
---|---|
Faculdade Evangelica do Parana |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Inspiratory muscle strength | 2 hours | No | |
Secondary | Exercise capacity | 2 hours | No |
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