European Non-interventional Study in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial

Official title:

Patient Perception of Symptom Variability. A Cross-sectional Study of Patients With Severe COPD.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00722267
• Other study ID #: NIS-REU-DUM-2007/1
• Status: Completed
• Start date: July 2008
• Est. completion date: February 2009

Study information

• Verified date: July 2009
• Source: AstraZeneca
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study is investigating how patients with severe stable state COPD perceive the variability of their symptoms throughout the day, the week and the year; the impact of these variations on their daily activities or sleep quality and how they deal with their treatments. For this purpose patients will be asked to answer a questionnaire over the phone

Recruitment information / eligibility

• Status: Completed
• Enrollment: 7400
• Est. completion date: February 2009
• Accepts healthy volunteers: No
• Gender: All
• Age group: 45 Years and older

Eligibility

Inclusion Criteria:

• Outpatients with a diagnosis of COPD

• FEV1<50% and FEV1/FVC<0.7 according to lung function data in medical records.

• Smoker or ex-smoker > 10 pack-years

• Informed consent obtained

Exclusion Criteria:

• Ongoing exacerbation of COPD or within the previous 3 months

• Any other significant respiratory disease (including asthma and allergic rhinitis)

Related Conditions & MeSH terms

• Chronic Obstructive Pulmonary Disease (COPD)
• Lung Diseases
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Locations

Country	Name	City	State
Austria	Research Site	Baden
Austria	Research Site	Feldbach
Austria	Research Site	Feldkirch
Austria	Research Site	Gussing
Austria	Research Site	Innsbruck
Austria	Research Site	Landeck
Austria	Research Site	Linz
Austria	Research Site	Linz-Urfahr
Austria	Research Site	Neusiedl am See
Austria	Research Site	Salzburg
Austria	Research Site	SchluSSlberg
Austria	Research Site	Steyr
Austria	Research Site	Thalheim/Wels
Austria	Research Site	Wels
Austria	Research Site	Wien
Austria	Research Site	Winden
Austria	Research Site	Wr.Neustadt
Austria	Research Site	Zwettl
Belgium	Research Site	Aalst
Belgium	Research Site	Antwerpen
Belgium	Research Site	Ath
Belgium	Research Site	Bertogne
Belgium	Research Site	Boussu
Belgium	Research Site	Carnieres
Belgium	Research Site	Chatelet
Belgium	Research Site	Courcelles
Belgium	Research Site	Duffel
Belgium	Research Site	Florennes
Belgium	Research Site	Gent
Belgium	Research Site	Geraardsbergen
Belgium	Research Site	Gosselies
Belgium	Research Site	Haine-Saint-Paul
Belgium	Research Site	Houthulst
Belgium	Research Site	Houtvenne
Belgium	Research Site	Izegem
Belgium	Research Site	Kortessem
Belgium	Research Site	Kraainem
Belgium	Research Site	Lauwe
Belgium	Research Site	Liege
Belgium	Research Site	Lokeren
Belgium	Research Site	Lommel
Belgium	Research Site	Micheroux
Belgium	Research Site	Mons
Belgium	Research Site	Montzen
Belgium	Research Site	Olsene
Belgium	Research Site	Oostende
Belgium	Research Site	Saive
Belgium	Research Site	Schaerbeek
Belgium	Research Site	Sint-Pieters-Woluwe
Belgium	Research Site	Vielsalm
Belgium	Research Site	Willebroek
Belgium	Research Site	Zomergem
Denmark	Research Site	Aalborg
Denmark	Research Site	Arhus
Denmark	Research Site	Brorup
Denmark	Research Site	Copenhagen S
Denmark	Research Site	Frederikssund
Denmark	Research Site	Fredriksberg
Denmark	Research Site	Grenaa
Denmark	Research Site	Helsingor
Denmark	Research Site	Holbaek
Denmark	Research Site	Holstebro
Denmark	Research Site	Hvidovre
Denmark	Research Site	Ikast
Denmark	Research Site	Jaegerspris
Denmark	Research Site	Middelfart
Denmark	Research Site	Oksbol
Denmark	Research Site	Praesto
Denmark	Research Site	Roskilde
Denmark	Research Site	Sindal
Denmark	Research Site	Skive
Denmark	Research Site	Svinninge
Denmark	Research Site	Thisted
Finland	Research Site	Hameenlinna
Finland	Research Site	Helsingin Kaupunki
Finland	Research Site	Kajaani
Finland	Research Site	Klaukkala
Finland	Research Site	Kuopio
Finland	Research Site	Lahti
Finland	Research Site	Lappeenranta
Finland	Research Site	Lohja
Finland	Research Site	Mikkeli
Finland	Research Site	Narpio
Finland	Research Site	Oulu
Finland	Research Site	Pietarsaari
Finland	Research Site	Pori
Finland	Research Site	Pyhajoki
Finland	Research Site	Sairaalamaki
Finland	Research Site	Seinajoki
Finland	Research Site	Tammisaari
Finland	Research Site	Tampere
Finland	Research Site	Turku
Finland	Research Site	Vaaksy
France	Research Site	Agde
France	Research Site	Aix en Provence
France	Research Site	Albi
France	Research Site	Amelie les Bains
France	Research Site	Angers
France	Research Site	Annecy
France	Research Site	Argentan
France	Research Site	Arles
France	Research Site	Armentiere
France	Research Site	Auchy les Mines
France	Research Site	Augny
France	Research Site	Aureilhan
France	Research Site	Avignon
France	Research Site	Babarthe Sur Leze
France	Research Site	Bandol
France	Research Site	Bar le Duc
France	Research Site	Bayonne
France	Research Site	Beauvais
France	Research Site	Belfort
France	Research Site	Bethune
France	Research Site	Beziers
France	Research Site	Bois Guillaume
France	Research Site	Bordeaux
France	Research Site	Bourg en Bresse
France	Research Site	Brest
France	Research Site	Caen
France	Research Site	Castelnau le Lez
France	Research Site	Castelnaudary
France	Research Site	Cerizay
France	Research Site	Chalon En Champagne
France	Research Site	Champs sur Marne
France	Research Site	Charleville Mezieres
France	Research Site	Chateauroux
France	Research Site	Clermont Ferrand
France	Research Site	Colmar
France	Research Site	Colomiers
France	Research Site	Corbeil Essones
France	Research Site	Creil
France	Research Site	Creteil
France	Research Site	Croix
France	Research Site	Cugnaux
France	Research Site	Cuise la Motte
France	Research Site	Denain
France	Research Site	Desseges
France	Research Site	Draguignan
France	Research Site	Echirolles
France	Research Site	Epernay
France	Research Site	Epinal
France	Research Site	Ferolles Attilly
France	Research Site	Foix
France	Research Site	Fontainebleau
France	Research Site	Forbach
France	Research Site	Giens
France	Research Site	Gonesse
France	Research Site	Grasse
France	Research Site	Graulhet
France	Research Site	Guingamp
France	Research Site	Harnes
France	Research Site	Hyeres
France	Research Site	Istres
France	Research Site	Juan les Pins
France	Research Site	La Baule
France	Research Site	La Destrousse
France	Research Site	La Grande Motte
France	Research Site	La Rochelle
France	Research Site	Laon
France	Research Site	Laval
France	Research Site	Le Brusc
France	Research Site	Le Chesnay
France	Research Site	Le Kremlin Bicetre
France	Research Site	Le Perreux sur Marne
France	Research Site	Lievin
France	Research Site	Lille
France	Research Site	Limoges
France	Research Site	Lomme
France	Research Site	Lourdes
France	Research Site	Luce
France	Research Site	Lyon
France	Research Site	Mamande
France	Research Site	Mandelieu la Napoule
France	Research Site	Marseille
France	Research Site	Maury
France	Research Site	Maxeville
France	Research Site	Mensignac
France	Research Site	Molsheim
France	Research Site	Mont de Marsan
France	Research Site	Montauban
France	Research Site	Montbeliard
France	Research Site	Montfermeil
France	Research Site	Montigny les Metz
France	Research Site	Morlaix
France	Research Site	Nantes
France	Research Site	Nevers
France	Research Site	Nice
France	Research Site	Nimes
France	Research Site	Niort
France	Research Site	Nogent sur Marne
France	Research Site	Obernai
France	Research Site	Olioules
France	Research Site	Orsay
France	Research Site	Paris
France	Research Site	Perpignan
France	Research Site	Pertuis
France	Research Site	Pierre Benite
France	Research Site	Plouzane
France	Research Site	Poitiers
France	Research Site	Pont Eveque
France	Research Site	Pontallier Sur Saone
France	Research Site	Ponteil Et Bresis
France	Research Site	Quimper
France	Research Site	Quincy Voisins
France	Research Site	Remiremont
France	Research Site	Renaze
France	Research Site	Rennes
France	Research Site	Roanne
France	Research Site	Rochefort Cedex
France	Research Site	Ronchin
France	Research Site	Rougegoutte
France	Research Site	Royan
France	Research Site	Rueil-Malmaison
France	Research Site	Saint Aubin Des Chateux
France	Research Site	Saint Feyre
France	Research Site	Saint-Aubin-les-Elbeuf
France	Research Site	Saint-Hilaire Agen
France	Research Site	Saintes
France	Research Site	Salome
France	Research Site	Saulnes
France	Research Site	Segre
France	Research Site	Selestat
France	Research Site	Soissons
France	Research Site	St Amand les Eaux
France	Research Site	St Cyr sur Loire
France	Research Site	St Die des Vosges
France	Research Site	St Etienne
France	Research Site	St Genis Laval
France	Research Site	St Jean d'Angely
France	Research Site	St Jean de Luz
France	Research Site	St Julien en Genevois
France	Research Site	St Mamert du Gard
France	Research Site	St Mandrier sur Mer
France	Research Site	St Michel
France	Research Site	St Priest
France	Research Site	St Priest en Jarez
France	Research Site	St Quentin
France	Research Site	St Romain La Motte
France	Research Site	St Rome de Cernon
France	Research Site	St Symphorien sur Coise
France	Research Site	Ste Severe Sur Indre
France	Research Site	Strasbourg
France	Research Site	Taden
France	Research Site	Tarbes
France	Research Site	Thionville
France	Research Site	Toul
France	Research Site	Toulon
France	Research Site	Toulouse
France	Research Site	Vabres Labaye
France	Research Site	Vannes
France	Research Site	Venerque
France	Research Site	Venissieux
France	Research Site	Verdun
France	Research Site	Villefranche
Germany	Research Site	Arnsberg
Germany	Research Site	Augsburg
Germany	Research Site	Bad Krozingen
Germany	Research Site	Bad Sooden-Allendorf
Germany	Research Site	Bad Vilbel
Germany	Research Site	Belm
Germany	Research Site	Bergisch Gladbach
Germany	Research Site	Berlin
Germany	Research Site	Bernau
Germany	Research Site	Bochum
Germany	Research Site	Bonn
Germany	Research Site	Borchen
Germany	Research Site	Borstel
Germany	Research Site	Brakel
Germany	Research Site	Burkhardtsdorf
Germany	Research Site	Castrop-Rauxel
Germany	Research Site	Delitzsch
Germany	Research Site	Dieburg
Germany	Research Site	Dreieich
Germany	Research Site	Dresden
Germany	Research Site	Eckental
Germany	Research Site	Elbingerode
Germany	Research Site	Eschwege
Germany	Research Site	Essen
Germany	Research Site	Frankenberg
Germany	Research Site	Frankfurt
Germany	Research Site	Franzburg
Germany	Research Site	Freiburg
Germany	Research Site	Freital
Germany	Research Site	Friedrichsthal
Germany	Research Site	Furstenfeldbruck
Germany	Research Site	Furth
Germany	Research Site	Gelnhausen
Germany	Research Site	Gelsenkirchen
Germany	Research Site	Gerolzhofen
Germany	Research Site	Haan
Germany	Research Site	Halle
Germany	Research Site	Haltern
Germany	Research Site	Hamburg
Germany	Research Site	Hannover
Germany	Research Site	Hemmingen
Germany	Research Site	Ingolstadt
Germany	Research Site	Kamen
Germany	Research Site	Kempten
Germany	Research Site	Kiel
Germany	Research Site	Koln
Germany	Research Site	Kothen
Germany	Research Site	Kronach
Germany	Research Site	Laichingen
Germany	Research Site	Leinach
Germany	Research Site	Leipzig
Germany	Research Site	Leopoldshohe
Germany	Research Site	Liebenau
Germany	Research Site	Ludenscheid
Germany	Research Site	Magdeburg
Germany	Research Site	Mammendorf
Germany	Research Site	Manching
Germany	Research Site	Marburg
Germany	Research Site	Marktheidenfeld
Germany	Research Site	Moers
Germany	Research Site	Muhlhausen
Germany	Research Site	Niesky
Germany	Research Site	Nurnberg
Germany	Research Site	Oranienburg
Germany	Research Site	Osnabruck
Germany	Research Site	Pfronten
Germany	Research Site	Pleystein
Germany	Research Site	Pocking
Germany	Research Site	Potsdam
Germany	Research Site	Puchheim
Germany	Research Site	Roth
Germany	Research Site	Ruhmannsfelden
Germany	Research Site	Saarbrucken
Germany	Research Site	Saerbeck
Germany	Research Site	Schwabach
Germany	Research Site	Schwedt
Germany	Research Site	Sebnitz
Germany	Research Site	Solingen
Germany	Research Site	Starzach
Germany	Research Site	Straubing
Germany	Research Site	Stuttgart
Germany	Research Site	Teterow
Germany	Research Site	Welver
Germany	Research Site	Westerland
Germany	Research Site	Wettin
Germany	Research Site	Wiesbaden
Germany	Research Site	Witten
Germany	Research Site	Zerbst
Greece	Research Site	Athens
Greece	Research Site	Chalkida
Greece	Research Site	Chania
Greece	Research Site	Drapetsona
Greece	Research Site	Florina
Greece	Research Site	Heraklio
Greece	Research Site	Ilioupoli
Greece	Research Site	Ithaki
Greece	Research Site	Kalamaria
Greece	Research Site	Kifissia
Greece	Research Site	Koropi
Greece	Research Site	Lamia
Greece	Research Site	Messini
Greece	Research Site	N.Santa
Greece	Research Site	Patra
Greece	Research Site	Platamonas
Greece	Research Site	Preveza
Greece	Research Site	Serres
Greece	Research Site	Thessaloniki
Greece	Research Site	Veroia
Ireland	Research Site	Cavan
Ireland	Research Site	Dublin
Ireland	Research Site	Enniscorthy
Ireland	Research Site	Gorey
Ireland	Research Site	Letterkenny
Ireland	Research Site	Mullingar
Ireland	Research Site	Turloughmore
Ireland	Research Site	Waterford
Italy	Research Site	Alife
Italy	Research Site	Avezzano
Italy	Research Site	Badolato
Italy	Research Site	Balsorano
Italy	Research Site	Carsoli
Italy	Research Site	Casa Giove
Italy	Research Site	Caserta
Italy	Research Site	Ceparana
Italy	Research Site	Copertino
Italy	Research Site	Cutrofiano
Italy	Research Site	Eboli
Italy	Research Site	Grosseto
Italy	Research Site	La Spezia
Italy	Research Site	Macerata Campania
Italy	Research Site	Montiano
Italy	Research Site	Napoli
Italy	Research Site	Orbetello
Italy	Research Site	Ortonovo
Italy	Research Site	Paganico
Italy	Research Site	Palermo
Italy	Research Site	Pellezzano
Italy	Research Site	Pontecagnano
Italy	Research Site	Rispescia
Italy	Research Site	S.Maria Di Cantanzzaro
Italy	Research Site	Salerno
Italy	Research Site	San Felice a Cancello
Italy	Research Site	San Nicola La Strada
Italy	Research Site	San Pietro in Lama
Italy	Research Site	Srubo
Italy	Research Site	Trasacco
Italy	Research Site	Veglie
Netherlands	Research Site	Almere
Netherlands	Research Site	Alphen Aan Den Rijn
Netherlands	Research Site	Amsterdam
Netherlands	Research Site	Andijk
Netherlands	Research Site	Arnhem
Netherlands	Research Site	Delfzijl
Netherlands	Research Site	Den Helder
Netherlands	Research Site	Drachten
Netherlands	Research Site	Enschede
Netherlands	Research Site	Gouda
Netherlands	Research Site	Groningen
Netherlands	Research Site	Heemstede
Netherlands	Research Site	Heerlen
Netherlands	Research Site	Hilversum
Netherlands	Research Site	Hoogwoud
Netherlands	Research Site	Landgraaf
Netherlands	Research Site	Leiden
Netherlands	Research Site	Meppel
Netherlands	Research Site	Onstwedde
Netherlands	Research Site	Oude Pekela
Netherlands	Research Site	Roermond
Netherlands	Research Site	Rotterdam
Netherlands	Research Site	S-Gravenhage
Netherlands	Research Site	S-Hertogenbosch
Netherlands	Research Site	Sint Philipsland
Netherlands	Research Site	Sneek
Netherlands	Research Site	Tilburg
Netherlands	Research Site	Utrecht
Netherlands	Research Site	Zutphen
Norway	Research Site	Alesund
Norway	Research Site	Brevik
Norway	Research Site	Hakadal
Norway	Research Site	Molde
Norway	Research Site	Oslo
Norway	Research Site	Trondheim
Portugal	Research Site	Coimbra
Portugal	Research Site	Lisboa
Portugal	Research Site	Melgaco
Portugal	Research Site	Odivelas
Portugal	Research Site	Santarém
Portugal	Research Site	Torres Vedras
Spain	Research Site	A Coruna
Spain	Research Site	Alamagro
Spain	Research Site	Alcal De Henares
Spain	Research Site	Alcoy
Spain	Research Site	Alicante
Spain	Research Site	Andujar
Spain	Research Site	Arcos De La Fortera
Spain	Research Site	As Pontes De Garcia Rodriguez
Spain	Research Site	Avila
Spain	Research Site	Aviles
Spain	Research Site	Badalona
Spain	Research Site	Baracaldo
Spain	Research Site	Barcelona
Spain	Research Site	Bellaterra
Spain	Research Site	Bilbao
Spain	Research Site	Boqueixon (Pontella)
Spain	Research Site	Brean Alta
Spain	Research Site	Burela
Spain	Research Site	Burgos
Spain	Research Site	Burguillos
Spain	Research Site	Carvaca De La Cruz
Spain	Research Site	Castellon de la Plana
Spain	Research Site	Cervera
Spain	Research Site	Cesuras
Spain	Research Site	Cuenca
Spain	Research Site	El Vendrell
Spain	Research Site	Ferrol
Spain	Research Site	Fuenlabrada
Spain	Research Site	Girona
Spain	Research Site	Granollers
Spain	Research Site	Guadalajara
Spain	Research Site	Huelva
Spain	Research Site	Jaen
Spain	Research Site	Joiosa
Spain	Research Site	La Almunia de Dona Godina
Spain	Research Site	Laredo
Spain	Research Site	Las Palmas De Gran Canaria
Spain	Research Site	Leganes
Spain	Research Site	Llobregat
Spain	Research Site	Logrono
Spain	Research Site	Lora Del Rio
Spain	Research Site	Lugo
Spain	Research Site	Madrid
Spain	Research Site	Manacor
Spain	Research Site	Melilla
Spain	Research Site	Mieres
Spain	Research Site	Montilla
Spain	Research Site	Murcia
Spain	Research Site	Outes
Spain	Research Site	Oviedo
Spain	Research Site	Palma De Mallorca
Spain	Research Site	Pamplona
Spain	Research Site	Ponferrada
Spain	Research Site	Porreres
Spain	Research Site	Portugalete
Spain	Research Site	Pozoblanco
Spain	Research Site	Quart de Poblet
Spain	Research Site	Quintanar Del Rey
Spain	Research Site	Ronda
Spain	Research Site	Sabadell
Spain	Research Site	Sagunto
Spain	Research Site	Salamanca
Spain	Research Site	Salt
Spain	Research Site	San Sebastian
Spain	Research Site	Sant Antoni de Portmany
Spain	Research Site	Sant Boi De Llobregat
Spain	Research Site	Sant Pere De Ribes
Spain	Research Site	Sant Vicent Del Raspeig
Spain	Research Site	santa Coloma de Gramenet
Spain	Research Site	Santa Coloma De Queralt
Spain	Research Site	Santiago De Compostella
Spain	Research Site	Santurtzi
Spain	Research Site	Teruel
Spain	Research Site	Toledo
Spain	Research Site	Torrebonica
Spain	Research Site	Torrelavega
Spain	Research Site	Valdepenas
Spain	Research Site	Valencia
Spain	Research Site	Valladolid
Spain	Research Site	Vigo
Spain	Research Site	Viladecans
Spain	Research Site	Xativa
Sweden	Research Site	Angered
Sweden	Research Site	Atvidaberg
Sweden	Research Site	Bjarred
Sweden	Research Site	Borlange
Sweden	Research Site	Danderyd
Sweden	Research Site	Falun
Sweden	Research Site	Forserum
Sweden	Research Site	Fredriksberg
Sweden	Research Site	Gavle
Sweden	Research Site	Goteborg
Sweden	Research Site	Hollviken
Sweden	Research Site	Hunnebostrand
Sweden	Research Site	Kalarne
Sweden	Research Site	Kinna
Sweden	Research Site	Kungsbacka
Sweden	Research Site	Malmo
Sweden	Research Site	Norrkoping
Sweden	Research Site	Ostersund
Sweden	Research Site	Stockholm
Sweden	Research Site	Sundsvall
Sweden	Research Site	Uppsala
Sweden	Research Site	Varnamo
Switzerland	Research Site	Bern
Switzerland	Research Site	Davos Wolfgang
Switzerland	Research Site	Herisau
Switzerland	Research Site	Lausanne
Switzerland	Research Site	Martigny
Switzerland	Research Site	Samedan
Switzerland	Research Site	Spiez
Switzerland	Research Site	Zurich
Turkey	Research Site	Adana
Turkey	Research Site	Akyokus-Konya
Turkey	Research Site	Anamur/mersin
Turkey	Research Site	Ankara
Turkey	Research Site	Aydin
Turkey	Research Site	Denizli
Turkey	Research Site	Erzincan
Turkey	Research Site	Eskisehir
Turkey	Research Site	Hatay
Turkey	Research Site	Istanbul
Turkey	Research Site	Izmir
Turkey	Research Site	K.Maras
Turkey	Research Site	Konya
Turkey	Research Site	Malatya
Turkey	Research Site	Mezitli-Mersin
Turkey	Research Site	Osmaniye
Turkey	Research Site	Sakarya
Turkey	Research Site	Sanliurfa
Turkey	Research Site	umraniye-Istanbul
Turkey	Research Site	Yenisehir
Turkey	Research Site	Yozgat
Turkey	Research Site	Zonguldak
United Kingdom	Research Site	Ashwell
United Kingdom	Research Site	Atherstone
United Kingdom	Research Site	Barry
United Kingdom	Research Site	Birmingham
United Kingdom	Research Site	Blackburn
United Kingdom	Research Site	Blackpool
United Kingdom	Research Site	Bradford-On-Avon
United Kingdom	Research Site	Cardiff
United Kingdom	Research Site	Chertsey
United Kingdom	Research Site	Chesterfield
United Kingdom	Research Site	Chippenham
United Kingdom	Research Site	Cookstown
United Kingdom	Research Site	Corsham
United Kingdom	Research Site	Coventry
United Kingdom	Research Site	Doncaster
United Kingdom	Research Site	Fife
United Kingdom	Research Site	High Valleyfield
United Kingdom	Research Site	Maidenhead
United Kingdom	Research Site	Nottingham
United Kingdom	Research Site	Peterborough
United Kingdom	Research Site	Plymouth
United Kingdom	Research Site	Ruislip
United Kingdom	Research Site	Sandy
United Kingdom	Research Site	Southampton
United Kingdom	Research Site	Sunbury on Thames
United Kingdom	Research Site	Thornton Heath
United Kingdom	Research Site	Trowbridge
United Kingdom	Research Site	Warminster
United Kingdom	Research Site	Wells next the Sea
United Kingdom	Research Site	Westbury

Sponsors (1)

Lead Sponsor	Collaborator
AstraZeneca

Countries where clinical trial is conducted

Austria,  Belgium,  Denmark,  Finland,  France,  Germany,  Greece,  Ireland,  Italy,  Netherlands,  Norway,  Portugal,  Spain,  Sweden,  Switzerland,  Turkey,  United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Patient's perception of the variability of symptoms due to severe stable state COPD throughout the day, the week and the year		Once
Secondary	Impact of symptoms (and variability of symptoms) on the patient's morning & daily living activities and sleep quality.		Once
Secondary	Describe how patient use their COPD treatment		Once
Secondary	Factors that may influence the patient's perception of symptom variability		Once