Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Arm Training in COPD: Short and Medium Term Effects on Dyspnoea, Health-related Quality of Life, Arm Function and Arm Exercise Capacity.
Verified date | February 2010 |
Source | West Park Healthcare Centre |
Contact | n/a |
Is FDA regulated | No |
Health authority | Canada: Ethics Review Committee |
Study type | Interventional |
Patients with chronic lung disease often report shortness of breath when they use their arms
for simple activities of daily living such as dressing, lifting, shaving, bathing and
brushing their hair and teeth. The best type of arm training for these patients is still
unknown.
The objectives of this study are to:
- develop a feasible and safe arm training program (ATP) for these patients;
- examine the effects of this ATP on quality of life, arm function, arm exercise capacity
and symptoms during activities of daily living;
- examine the effects of ATP on breathing responses during arm exercises.
Status | Completed |
Enrollment | 34 |
Est. completion date | January 2010 |
Est. primary completion date | January 2010 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - a diagnosis of COPD - a forced expiratory volume in one second (FEV1) of less than 80% the predicted normal value - must report dyspnoea during at least one activity of daily living that requires arm activity - must have a smoking history greater than 10 pack years and - must be able to provide written informed consent Exclusion Criteria: - acute exacerbation of COPD that required a change in pharmacological management within the preceding two months - an inability to understand English - cognitive impairment - requirement for mechanical ventilation for all or part of the day - tapering doses of oral corticosteroids or xanthines - evidence of a musculoskeletal or neurological condition which could adversely affect arm exercise performance - symptomatic ischemic cardiac disease - a history of previous lung surgery and alpha1 antitrypsin deficient emphysema |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Canada | West Park Healthcare Centre | Toronto | Ontario |
Lead Sponsor | Collaborator |
---|---|
West Park Healthcare Centre |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Feasibility measures, dyspnoea during activities of daily living, fatigue, health-related quality of life, unsupported arm exercise capacity, arm function and peripheral muscle force | Primary outcome measures will be collected before PR program, on completion of the PR program (at 6 weeks) and at three months following completion of the PR program. | No | |
Secondary | Peak cardiorespiratory responses during incremental unsupported upper limb exercise test | Secondary outcome measures will be collected before PR program, on completion of the PR program (at 6 weeks) and at three months following completion of the PR program. | No |
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