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NCT00568100 Clinical Trial

Effect of Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist (NAVA) in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease Clinical Trial

Official title:
Effect of Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist (NAVA) in COPD Patients

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00568100
Other study ID # 2222
Secondary ID
Status Completed
Phase N/A
First received December 4, 2007
Last updated April 27, 2015
Start date April 2010
Est. completion date November 2014

Study information
Verified date April 2015
Source Policlinico Hospital
Contact n/a
Is FDA regulated No
Health authority Italy: Ministry of Health
Study type Interventional

Clinical Trial Summary

The investigators' aim is to study the effect of pressure support ventilation at two levels of PEEP and Pressure Support versus neurally adjusted ventilatory assist (NAVA) in COPD patients.

Description:

In this study, two levels of pressure support and PEEP during pressure support ventilation are compared with neurally adjusted ventilatory assist (NAVA) in COPD patients by measuring respiratory mechanics, intrinsic PEEP, work of breathing and patient's level of comfort.

Recruitment information / eligibility
Status Completed
Enrollment 15
Est. completion date November 2014
Est. primary completion date November 2014
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Stable COPD patients during non invasive mechanical ventilation

Exclusion Criteria:

- Haemodynamic instability

- Coma

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Procedure:
• PSV and NAVA
evaluated the effect of PSV and NAVA on breathing pattern, respiratory effort, gas exchange and level of breathing comfort in COPD patients

Locations
Country Name City State
Italy Policlinico Hospital Milano

Sponsors (1)
Lead Sponsor Collaborator
Policlinico Hospital

Country where clinical trial is conducted

Italy, 

Outcome
Type Measure Description Time frame Safety issue
Primary Respiratory mechanics, gas exchange, work of breathing 5 minutes No
Secondary Comfort of breathing 5 minutes No
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