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Mitochondrial Dysfunction and Oxidative Stress in Chronic Obstructive Pulmonary Disease (COPD) Patients

COPD Patients Clinical Trial

Official title:
Mitochondrial Respiratory Chain and Peripheral Muscle Dysfunction in COPD Patients

Clinical Trial Summary

The purpose of this study is to understand the underlying mechanisms of improved exercise tolerance in COPD patients after training program.

Clinical Trial Description

Training protocol used is based on recommendations (Nici et al., 2006) and was previously used in our group (Varray et al., 1991; Vallet et al., 1997). A minimum of 20 sessions in 4-6 weeks were proposed. The exercise intensity of exercise corresponds to target heart rate at ventilatory threshold measured during incremental exercise test. Training at this intensity allowed us to individualize effort for each patient. ;

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01183052
Study type Interventional
Source 5 Santé
Contact
Status Completed
Phase N/A
Start date June 2009
Completion date December 2010
View Details
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