COPD Exacerbation Clinical Trial
Official title:
Effect of Noninvasive High Frequency Oscillatory Ventilation on Improving Carbon Dioxide Clearance in COPD Patients : a Clinical Crossover Trial
High-frequency oscillatory ventilation (HFOV), as an ideal lung-protecting ventilation method, has been gradually used in neonatal critical care treatment, and is currently recommended as a rescue method for neonatal acute respiratory distress syndrome (ARDS) after failure of conventional mechanical ventilation. . Although its ability to improve oxygenation and enhance carbon dioxide (CO2) scavenging has been repeatedly demonstrated in laboratory studies, its impact on clinical outcomes in these patients remains uncertain. Non-invasive high-frequency oscillatory ventilation (nHFOV) combines the advantages of HFOV and non-invasive ventilation methods, and has become a current research hotspot in this field. It is recommended to be used to avoid intubation after conventional non-invasive ventilation therapy fails. For the treatment of intubation, there is still a lack of large-scale clinical trials to systematically explore its efficacy. The gradual increase in the clinical application of nHFOV has also enriched its use in the treatment of other diseases
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Enrolling by invitation |
NCT06000696 -
Healthy at Home Pilot
|
||
| Recruiting |
NCT03250000 -
Changes in Microcirculation and Functional Status During Exacerbation of COPD
|
N/A | |
| Recruiting |
NCT04142827 -
The Effect of Long Term Therapy With High Flow Humidification Compared to Usual Care in Patients With Bronchiectasis (BX)
|
N/A | |
| Recruiting |
NCT05865184 -
Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD
|
||
| Completed |
NCT01892566 -
Using Mobile Health to Respond Early to Acute Exacerbations of COPD in HIV
|
N/A | |
| Completed |
NCT04119856 -
Outgoing Lung Team - a Cross-sectorial Intervention in Patients With COPD
|
N/A | |
| Recruiting |
NCT06118632 -
Physiological and Environmental Data in a Remote Setting to Predict Exacerbation Events in Patients With Chronic Obstructive Pulmonary Disease
|
||
| Recruiting |
NCT04860375 -
Multidisciplinary Management of Severe COPD
|
N/A | |
| Completed |
NCT04170361 -
The Effect of Incentive Spirometry Added to Routine Physiotherapy Program on Hemodynamic Responses and Hospital Stay in Patients With COPD Exacerbation
|
N/A | |
| Not yet recruiting |
NCT03696563 -
FreeO2 PreHospital - Automated Oxygen Titration vs Manual Titration According to the BLS-PCS
|
N/A | |
| Not yet recruiting |
NCT03296215 -
Pattern of Admitted Cases in Respiratory Intensive Care Unit at Assiut University Hospitals
|
N/A | |
| Completed |
NCT03003702 -
Domiciliary Monitoring to Predict Exacerbations of COPD
|
N/A | |
| Completed |
NCT02912689 -
NIV - NAVA vs NIV - PS for COPD Exacerbation
|
N/A | |
| Recruiting |
NCT02264483 -
Low-dose CT for Diagnosis of Pneumonia in COPD Exacerbations and Comparison of the Inflammatory Profile.
|
N/A | |
| Completed |
NCT01443845 -
Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)
|
Phase 4 | |
| Recruiting |
NCT02065921 -
Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort
|
||
| Completed |
NCT04880486 -
Weight Training With VR in Out-Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
|
N/A | |
| Recruiting |
NCT03286127 -
Palliative Outcome Evaluation Muenster I
|
||
| Recruiting |
NCT04638920 -
Molecular Breath Print of COPD Patients With Exacerbations Despite Triple Inhalational Therapy
|
||
| Recruiting |
NCT06304207 -
Telehealth and Onsite Maintenance Exercise in COPD
|
N/A |