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Contact Lens Complication clinical trials

View clinical trials related to Contact Lens Complication.

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NCT ID: NCT04163328 Active, not recruiting - Dry Eye Clinical Trials

Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort

Start date: September 16, 2022
Phase: Phase 4
Study type: Interventional

HydroEye® is a dietary supplement that contains both EPA and DHA, as well as GLA and ALA in the form of black currant seed oil. It also has vitamins A, E, C, B6, and magnesium, many of which are involved in fatty acid metabolism. In 2013, Sheppard et al. tested HydroEye® in dry eye patients who were not contact lens wearers and found that symptoms and corneal smoothness improved in response to HydroEye® supplementation. To date, HydroEye® has not been assessed in patients with contact lens discomfort; therefore, the purpose of this clinical trial is to determine the efficacy of HydroEye® as a treatment for contact lens discomfort.

NCT ID: NCT03848221 Completed - Dry Eye Clinical Trials

Direct Application of Systane Complete to Contact Lenses

Start date: May 28, 2019
Phase: Phase 4
Study type: Interventional

A common first line treatment for patients with dryness symptoms or contact lens discomfort is the application of artificial tears or rewetting drops, respectively. Rewetting drops are specifically formulated for use with contact lenses while artificial tears are indicated for dry eye. Modern rewetting drops and artificial tears have similar formulations with similar preservatives, preservatives that have been shown to be compatible with contact lenses. While rewetting drops and artificial tears are regulated under different U.S. Food & Drug Administration policies, artificial tears are not specifically indicated for direct use with contact lenses. Nevertheless, clinicians commonly prescribe artificial tears to contact lens wearers likely because newer formulations of artificial tear have the potential to outperform available rewetting drops. The safety and efficacy of using artificial tears with contact lenses for the treatment of discomfort is supported by Caffery and Josephson and Ozkan and Papas who found that artificial tears significantly reduces dryness symptoms in contact lens wearers. Thus, the purpose of this study is to test the safety of directly applying a new artificial tear, Systane Complete, to the contact lens wearing eye and its ability to alleviate symptoms while wearing contact lenses during the day.

NCT ID: NCT03566680 Completed - Dry Eye Clinical Trials

Treating Contact Lens Discomfort With Orthokeratology

Start date: August 7, 2018
Phase: N/A
Study type: Interventional

The primary aim of this study is to understand if orthokeratology can be used to improve contact lens comfort and the secondary aim is understand patient adaptation to orthokeratology.

NCT ID: NCT03525704 Completed - Clinical trials for Contact Lens Complication

Evaluation of Contact Lens Saline Solutions With Scleral GP Contact Lens Wearers Experiencing Fogging

Start date: April 9, 2018
Phase: N/A
Study type: Interventional

Evaluation of saline solutions used with scleral rigid gas permeable contact lens wearers experiencing debris in the post lens tear reservoir

NCT ID: NCT03408015 Withdrawn - Dry Eye Clinical Trials

Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease

Start date: January 2019
Phase: Phase 4
Study type: Interventional

Every night during sleep, there is an accumulation of white blood cells in the closed eye. The closed eye white blood cells are predominantly neutrophils, but there is a small population (3%) of T cells. The effects of these closed eye white blood cells on dry eye disease pathogenesis have yet to be fully elucidated, but preliminary evidence suggests that closed eye neutrophils may have an associated hyperactivity and increased degranulation in dry eye disease that could contribute to epithelial instability. As an anti-T cell therapy, Xiidra offers an opportunity to better understand how the closed eye white blood cells are recruited and activated. This study also seeks to verify the proposed mechanism of action.

NCT ID: NCT03305484 Completed - Clinical trials for Contact Lens Complication

Soft Contacts Observation of Risk and Education (SCORE)

SCORE
Start date: December 30, 2017
Phase:
Study type: Observational

Specific Aims 1. Develop risk assessment scores for SCL wearers 2. Test the scoring algorithm in SCL wearers who present with adverse events 3. Explore targeted patient education to reduce risk behaviors associated with SCL wear.

NCT ID: NCT02298400 Withdrawn - Clinical trials for Contact Lens Complication

A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses

Start date: August 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the comfort of three commercially available contact lenses.