Contact Dermatitis Clinical Trial
Official title:
Randomized Controlled Trial of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis
Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM. Healthy volunteers will be included (at least 25) and test sites are forearms. Sodium lauryl sulphate will be used to induce contact dermatitis and participants will be measured for 7 days
| Status | Recruiting |
| Enrollment | 25 |
| Est. completion date | July 2024 |
| Est. primary completion date | June 2024 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 18 Years to 50 Years |
| Eligibility | Inclusion Criteria: - young, healthy volunteers who gave written informed consent Exclusion Criteria: - skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation |
| Country | Name | City | State |
|---|---|---|---|
| Croatia | University of Split School of Medicine | Split |
| Lead Sponsor | Collaborator |
|---|---|
| University of Split, School of Medicine |
Croatia,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | tewameter | measurement of transepidermal water loss on skin, objective and non invasive | day 1- day 7 |
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