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Constriction, Pathologic clinical trials

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NCT ID: NCT05251012 Completed - Clinical trials for Coronary Artery Disease

3D-QFR in Non-selected Angiographic Stenosis. A Spanish Multicentre Study.

Start date: January 1, 2015
Phase:
Study type: Observational

Physiology-based decision-making about the need for revascularisation in patients with stable coronary heart disease has consistently proven better clinical outcomes than a merely anatomical approach. However, against the current recommendations, revascularisation in most of patients with chronic coronary syndromes still relies on coronary angiography alone. The increase in costs and in procedural complexity of wire-based physiology may explain the latter. Therefore, a novel non-invasive functional quantitative flow ratio (QFR) index was created in order to solve it. A retrospective and multicentre study is performed to assess the 5-year prognosis of patients undergoing coronary angiography through a centralized QFR analysis. Consecutive participants with confirmed or suspected diagnosis of stable coronary disease who underwent a coronary angiography between 01/01/2015 and 12/31/2015 were included. Aims of the study: - To evaluate the prognosis of stable coronary disease depending on the functional assessment of coronary artery disease. - To determine the % of percutaneous coronary interventions that could be avoided if this study had been carried out through functional assessment of coronary artery disease based on 3-dimensional vessel reconstruction.

NCT ID: NCT05250193 Completed - Coronary Stenosis Clinical Trials

DK Score Coronary Scoring Balloon: a RCT Trial to Evaluate Acute Lumen Gain (SCORE CHINA)

Start date: March 24, 2021
Phase: N/A
Study type: Interventional

A prospective, Multi-center, Randomized Study designed to evaluate the acute lumen gain and device procedural success of the DK ScoreTM Scoring balloon versus NSE Scoring Balloon for patients with coronary arteries stenosis.

NCT ID: NCT05248087 Completed - Constriction Clinical Trials

Pain, Discomfort, and Functional Impairments During Maxillary Expansion

Start date: February 20, 2020
Phase: N/A
Study type: Interventional

Maxillary expansion is associated with varying degrees of pain and functional impairments. The current study aims to compare rapid maxillary expansion using a McNamara-type (bonded) appliance and slow maxillary expansion using a removable palatal expansion appliance concerning patient-centered outcomes. Those outcomes will include pain and discomfort, mastication difficulties, swallowing difficulties, and pressure on the soft tissues.

NCT ID: NCT05203666 Completed - Clinical trials for Degenerative Lumbar Spinal Stenosis

Clinical and Radiological Outcomes Following Insertion of a Novel Removable Percutaneous Interspinous Process Spacer: an Initial Experience.

LOBSTER
Start date: January 1, 2021
Phase:
Study type: Observational

Purpose To evaluate clinical and radiologic outcome of a series of patients treated with a removable percutaneous interspinous process spacer (IPS) (LobsterProject® Techlamed®) for symptomatic degenerative lumbar spinal stenosis (DLSS). Methods All patients treated in the two considered Centres with this IPS during 2019 were retrospectively reviewed. Patients with incomplete clinical or radiological documentation were not included. Procedures were performed under deep sedation or general anaesthesia by two interventional radiologists. Patients were clinically evaluated before intervention and at 3-month follow-up with Visual Analog Scale for pain (VAS), Oswestry Disability Index (ODI) and radiologically with MRI or CT scans. Neural foramina were independently measured for each patient on pre- and post-procedural CT scans by two radiologists.

NCT ID: NCT05140733 Completed - Clinical trials for Lumbar Foraminal Stenosis

Outcomes of Patients With Foraminal Stenosis

Start date: August 22, 2021
Phase:
Study type: Observational

The present study was to see the effect of minimally invasive neural foraminotomy for lumbar foraminal stenosis with unilateral radicular pain. Traditionally, fusion was was done for the patients, but recent development enable surgeon to decompress neural foramen without rigid spinal fusion. Although, clinical effect of neural foraminotomy may have limitation in attaining a comparable result to fusion surgery, a cost-effective analysis may reveal a result in a different perspective. In this regard, we designed a prospective cohort study to see the cost-effectiveness of neural foraminotomy compared to fusion surgery.

NCT ID: NCT05078788 Completed - Urethral Stricture Clinical Trials

Holmium Laser Uretherotomy in Combination With Intralesional Steroids in Bulbar Uretheral Stricture

Start date: June 2, 2020
Phase: N/A
Study type: Interventional

the purpose is to evaluate the outcome of visual internal uretherotomy with Holmium laser along with intralesional steroid injection.

NCT ID: NCT05018962 Completed - Clinical trials for Dialysis Access Malfunction

Recurrent Stenoses in Arteriovenous Fistula (AVF) for Dialysis Access: CuttIng ballooN angioplaSTy Combined wITh Paclitaxel drUg coaTed Balloon Angioplasty, an observatIONal Clinical Study

INSTITUTION
Start date: September 8, 2017
Phase: Phase 2
Study type: Interventional

To determine if cutting balloon angioplasty combined with DEB angioplasty provides a higher primary patency after treatment of recurrent stenoses compared with cutting balloon angioplasty or angioplasty using DEB alone in the venous outflow AVFs. For cutting balloon angioplasty in venous stenosis, the primary patency after 12 months is 55-60% (9,16) and in recurrent stenoses up to 48%(10). We hypothesise that DEB angioplasty after cutting balloon angioplasty leads to improved primary patency at 12 months.

NCT ID: NCT05002088 Completed - Clinical trials for Aortic Valve Stenosis

Portico Valve-in-Valve Retrospective Registry

Start date: October 21, 2021
Phase:
Study type: Observational [Patient Registry]

The objective of this data-collection study is to retrospectively evaluate the safety and clinical performance of the Portico transthoracic aortic valve for Valve-in-Valve treatment of a failed aortic surgical bioprosthetic valve in patients who are considered at increased surgical risk for a redo surgical aortic valve replacement.

NCT ID: NCT04985773 Completed - Coronary Stenosis Clinical Trials

A Study to EXhibit Percutaneous Coronary Artery Dilatation With Non-Slip Element Balloon

EXPANSE-PTCA
Start date: December 17, 2021
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate safety and effectiveness of the Lacrosse NSE ALPHA coronary dilatation catheter during PCI in subjects with stenotic coronary arteries.

NCT ID: NCT04812444 Completed - Iliac Vein Stenosis Clinical Trials

Peripheral Venous Stent System in the Treatment of Iliac Vein Stenosis or Occlusion

Start date: October 9, 2020
Phase: N/A
Study type: Interventional

Clinical study on safety and efficacy of Zylox peripheral venous stent system in the treatment of iliac vein stenosis or occlusion.