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Constriction, Pathologic clinical trials

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NCT ID: NCT04112108 Completed - Clinical trials for Mitral Valve Stenosis

Late Clinical Outcomes of Percutaneous Mitral Commissurotomy in Patients With Mitral Stenosis

Start date: March 1, 2017
Phase:
Study type: Observational [Patient Registry]

In this retrospective cohort study, out of 220 patients who had undergone successful PTMC between 2006 and 2018, the clinical course of 186 patients could be successfully followed. Peri-procedural clinical and echocardiographic data were collected for these patients. Cardiac-related death, undergoing a second PTMC or mitral valve replacement (MVR) were considered adverse cardiac events in follow-up for the purpose of this study. Patients with no history of these events were contacted and asked to undergo echocardiographic imaging, in order to assess the prevalence of mitral valve restenosis, defined as mitral valve area (MVA) < 1.5 cm2 and loss of ≥50% of initial area gain

NCT ID: NCT04112030 Completed - Bile Duct Stricture Clinical Trials

Role of DIA in Diagnosing Nature of Indeterminate Biliary Duct Stricture

Start date: October 2016
Phase:
Study type: Observational

The study aimed to assess role of DIA in diagnosing nature of indeterminate bile ducts stricture

NCT ID: NCT04103931 Completed - Clinical trials for Aortic Valve Stenosis

Impact of a Patient Decision Aid for Treatment of Aortic Stenosis

Start date: September 23, 2019
Phase: N/A
Study type: Interventional

This project will evaluate the impact of a patient decision aid created by the American College of Cardiology for patients considering treatment of aortic stenosis. The decision aid describes surgical aortic valve replacement (SAVR) surgery and transcatheter valve replacement surgery (TAVR).

NCT ID: NCT04098523 Completed - Clinical trials for Abdominal Aortic Aneurysm

Prevalence of Carotid Artery Stenosis and Abdominal Aortic Aneurysms in Brussels: a Population-based Screening Study.

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Both abdominal aortic aneurysm (AAA) and carotid artery stenosis (CAS) are frequent clinical entities, with major morbidity and mortality. This project obtains robust data on the prevalence of AAA and CAS in the Brussels Capital Region. Using duplex ultrasound, a low invasive examination, we want to obtain information on a vast sample of men and women of the Brussels capital region, starting at the age of 60. With these data we can have a far better view on the Belgian situation of these two main vascular clinical entities. The data can provide insights on if, and how, Belgian public health policy can be improved concerning AAA and CAS.

NCT ID: NCT04094220 Completed - Clinical trials for Lumbar Spinal Stenosis

LLIF Plus Posterior Decompression for Severe Lumbar Spinal Stenosis

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Lateral lumbar interbody fusion (LLIF), as a minimally invasive technique, is an indirect decompression technique, and its decompression effect is not as thorough as traditional posterior decompression surgery. For certain patients with severe lumbar stenosis, additional posterior decompression is required. However, whether additional posterior decompression is necessary for these patients is unknown. Radiographic predictors of failed indirect decompression via LLIF is unknown. In current randomized, controlled trial , the investigators compare the clinical outcomes of patients with severe lumbar stenosis who received LLIF plus posterior decompression and those without posterior decompression.

NCT ID: NCT04087694 Completed - Clinical trials for Lumbar Spinal Stenosis

Microdecompression Versus Open Laminectomy and Posterior Stabilization for Multilevel Lumbar Spine Stenosis

Start date: January 3, 2016
Phase: N/A
Study type: Interventional

This study compare the results of 2 methods in surgical treatment of Lumbar spine stenosis.These are microdecompresssion and open decompression with posterior stabilization. 100 patients are involved in this study who divided in 2 groups.Each group was treated with one method and follow up done which showed both method are effective with better results in those patients treated with microdecomppression.

NCT ID: NCT04070365 Completed - Clinical trials for Peripheral Artery Disease

FLEX Arteriovenous Access Registry

Start date: May 28, 2018
Phase:
Study type: Observational [Patient Registry]

Evaluation of the FLEX Vessel Prep system combined with angioplasty in the treatment of arteriovenous access stenosis.

NCT ID: NCT04066634 Completed - Aortic Stenosis Clinical Trials

Vivio AS (Aortic Stenosis) Detection Study

Start date: April 2, 2019
Phase: N/A
Study type: Interventional

Evaluate the sensitivity and specificity of the Vivio System when used as an aid in the identification of heart sounds associated with severe aortic stenosis.

NCT ID: NCT04062474 Completed - Spinal Stenosis Clinical Trials

Epidural Intervention of Spinal Nerves With Tumor Necrosis Factor-Alpha Inhibitor

Start date: May 15, 2016
Phase: N/A
Study type: Interventional

This study is to assess the clinical efficacy of epidural injections with Tumor Necrosis Factor-Alpha(TNF-α) Inhibitor in patients with chronic radicular pain caused by lumbar spinal stenosis.

NCT ID: NCT04058223 Completed - Bleeding Clinical Trials

Comparison of the Short-term Outcomes of Using DST and PPH Staplers in the Treatment of Grade III and IV Hemorrhoids

Start date: September 5, 2018
Phase:
Study type: Observational

The hemorrhoidal disease affects approximately 4.4%-36% of the general population, and it has been estimated that >50% of the population aged >50 years experiences hemorrhoidal problems . Traditional hemorrhoidectomy, including Milligan-Morgan, Ferguson, and Whitehead procedures , are known to cause significant postoperative pain and discomfort and result in a poor quality of life after operation. Since the first introduction of the novel procedure hemorrhoidopexy by Longo in 1998, it has been considered as a safe procedure causing less postoperative pain and resulting in earlier recovery; furthermore, the patients are able to resume their normal daily life and work. The PPH stapler (Ethicon Endo-Surgery, Inc. Cincinnati, OH, USA) was also first introduced in 1998 as a device to perform this procedure. Subsequently, a new device, the DST stapler (Covidien, Mansfield, MA, USA), was introduced in 2008 with some structural differences, including a detachable anvil, three anchor points over different levels, a larger case, and different agraffe sizes. However, the majority of current studies have been focusing on the use of PPH stapler for hemorrhoidopexy, and comparison with the DST stapler has been rarely discussed. One randomized controlled trial that compared between the PPH stapler and the DST stapler reported that the DST stapler demonstrated a better hemostatic ability and allowed the resection of a larger area of mucosal prolapse; however, that trial focused only on bleeding among the postoperative complications. Currently, only a limited number of studies have compared these two devices in terms of pain, complications, and anorectal stricture incidence rate. The present investigation is a matched cohort-control study aimed to compare the postoperative short-term outcomes among patients with grade III and IV hemorrhoids who were treated with either the PPH or the DST stapler. The specimen surface area and the relationships with complications were also analyzed.