Clinical Trials Logo

Constriction, Pathologic clinical trials

View clinical trials related to Constriction, Pathologic.

Filter by:
  • Active, not recruiting  
  • Page 1 ·  Next »

NCT ID: NCT06457399 Active, not recruiting - Airway Obstruction Clinical Trials

Heliox on the Work of Breathing in Adult Patients With Lower Airway Stenosis

Start date: April 27, 2022
Phase:
Study type: Observational

Heliox (a mixture of Helium and Oxygen) can reduce the work of breathing in patients with airway stenosis by modifying turbulent flow into laminar flow. The aim of this study was to analyze the effect of Heliox versus conventional oxygen therapy in patients with lower airway stenosis on muscular effort measured by electromyography and diaphragmatic ultrasound, thoracoabdominal synchrony assessed with plethysmographic bands, dyspnea, stridor, oxygen saturation, transcutaneous carbon dioxide value, blood pressure, heart rate and respiratory rate.

NCT ID: NCT06446674 Active, not recruiting - Punctal Stenosis Clinical Trials

Comparison Between Mini Monaka,Perforated Plugs and 3-Snip Punctoplasty in Punctal Stenosis

Start date: May 25, 2024
Phase:
Study type: Observational

To compare the result of mini monaka to perforated plug and 3 snip punctoplasty in management of punctal stenosis.

NCT ID: NCT06365229 Active, not recruiting - Clinical trials for Lumbar Spinal Stenosis

Percutaneous Unilateral Biportal Endoscopy Versus Uniportal Endoscopy for Lumbar Spinal Stenosis: Study Protocol

Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

A prospective study aimed to compare the efficacy and safety of Unilateral biportal endoscopic (UBE) technique and uniportal endoscopic (UE) technique for treating patients with lumbar spinal stenosis (LSS).

NCT ID: NCT06281041 Active, not recruiting - Clinical trials for Coronary Artery Disease

Nationwide Cohort Study of Antiplatelet Agents as Primary Prevention

NHIS
Start date: January 1, 2013
Phase:
Study type: Observational

There is no specific recommendation regarding pharmacologic treatment as primary prevention for patients with intermediate coronary artery stenosis whose revascularization was deferred based on negative fractional flow reserve (FFR). Current nationwide cohort study conducted using Korean National Health Insurance Service database evaluated the safety and efficacy of antiplatelet therapy in patients with intermediate coronary artery stenosis with deferred revascularization based on negative FFR (FFR>0.80).

NCT ID: NCT06056206 Active, not recruiting - Clinical trials for Arteriovenous Fistula Stenosis

The SIR-POBA Shunt Trial

Start date: September 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare plain old balloon angioplasty with sirolimus-coated balloon angioplasty in patients with an arteriovenous shunt stenosis. The main question we aim to answer is, how patency is affected by each of the randomised treatment modality.

NCT ID: NCT06056193 Active, not recruiting - Clinical trials for Peripheral Arterial Occlusive Disease

The SIR-POBA Bypass Trial

Start date: September 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare plain old balloon angioplasty with sirolimus-coated balloon angioplasty in patients with an infrainguinal venous bypass stenosis. The main question we aim to answer is, how patency is affected by each of the randomised treatment options.

NCT ID: NCT06036680 Active, not recruiting - Crohn Disease Clinical Trials

Long-term Study of Endoscopic Treatment of Stenosis in Crohn´s Disease

Long-ProtDilat
Start date: December 19, 2022
Phase:
Study type: Observational

Stenosis is one of the most frequent complications in patients with Crohn's disease (CD), causing greater morbidity and increasing the probability of repeated surgery and short bowel syndrome. Several endoscopic techniques, as an alternative to surgery, have been used in the treatment of fibrostenotic CD, with similar efficacy and lower risk of complications. The ProtDilat study (NCT02395354) showed that both endoscopic balloon dilation (EBD) and self-expandable metal stents (SEMS) are efficient and safe for the treatment of stenosis in CD, while EBD shows therapeutic superiority (80.5 vs 51.3 %) at one year follow-up. However, this difference was not observed in the subanalysis of patients with stenosis > 3 cm (EBD: 66.7% vs SEMS: 63.6%) but with a lower cost for EBD (EDB 1,365.63 euros versus SEMS 1,923.55 euros). Therefore, SEMS could be a suitable treatment option for longer stenoses in which EBD has proven to be less efficacious. Moreover, the long-term efficacy of both endoscopic treatments is still debated with scare information and without data from a clinical trial. The aim of this study is to assess the long-term efficacy of EBD and SEMS, through the follow-up of the patients included in the ProtDilat study, being the primary objective of the study the percentage of patients free of surgical intervention at the end of follow-up. Retrospective study based on data from the ProtDilat trial (patients with CD, obstructive symptoms, with stenosis < 10cm). Data on medical, endoscopic and surgical treatment and smoking habits are collected.

NCT ID: NCT05826639 Active, not recruiting - Biliary Stricture Clinical Trials

A Study of Endobiliary Radiofrequency Ablation in Malignant Biliary Obstructions

Start date: April 13, 2023
Phase:
Study type: Observational

The purpose of this study is to assess the impact of temperature-sensitive radiofrequency ablation (RFA) immediately before biliary stent placement on duration of biliary stent patency and re-intervention free survival. This is a research study meant to collect information to help other patients with malignant biliary strictures in the future.

NCT ID: NCT05734157 Active, not recruiting - Clinical trials for Femoral Artery Occlusion

CVT-SFA First in Human Trial for Treatment of Superficial Femoral Artery or Proximal Popliteal Artery

Start date: February 17, 2022
Phase: N/A
Study type: Interventional

The CVT-SFA Trial investigates the inhibition of restenosis using the CVT Everolimus-coated PTA Catheter in the treatment of de-novo occluded/ stenotic or re-occluded/restenotic superficial femoral or popliteal arteries.

NCT ID: NCT05712161 Active, not recruiting - Aortic Stenosis Clinical Trials

Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility Study

DurAVR™ EFS
Start date: August 7, 2023
Phase: N/A
Study type: Interventional

To evaluate the safety and feasibility of DurAVR™ THV System in the treatment of subjects with symptomatic severe native aortic stenosis.