Optimization of Postoperative Bowel Habits

Constipation Clinical Trial

Official title: Optimization of Postoperative Bowel Habits Following Pelvic Reconstructive Surgery: a Randomized Controlled Trial

Status Not yet recruiting

Clinical Trial Summary

Project is a trial, in which women undergoing vaginal surgery for pelvic organ prolapse will be randomized 1:1 to a postoperative bowel regimen of either oral senna or rectal bisacodyl suppository.

Clinical Trial Description

Delayed return to bowel function following vaginal surgery for pelvic organ prolapse has been deemed to be highly distressing for patients, and is ranked as one of the most common reasons for emergency department visits and telephone calls in the immediate post-operative period.

Despite the prevalence of constipation and significant effect on quality of life, few studies have examined an evidence-based bowel regimen for postoperative constipation prevention in the Urogynecology population.

As per available medical literature, the onset of action for oral senna occurs within 6-12 hours, while bisacodyl suppository can take effect between 15 and 60 minutes following rectal administration. Proposed trial comparing oral senna to rectal bisacodyl suppositories for the prevention of postoperative constipation in women undergoing vaginal reconstructive surgery for symptomatic prolapse. ;

Related Conditions & MeSH terms

• Constipation

• NCT number: NCT06335797
• Study type: Interventional
• Source: Wake Forest University Health Sciences
• Contact: Christina M Mezes, MD
• Phone: 336-713-4098
• Email: cmezes@wakehealth.edu
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 2024
• Completion date: December 2025