Constipation Clinical Trial
Official title:
Maintenance Treatment With Polyethylene Glycol 3350 for Children With Constipation. A Randomized, Placebocontrolled Intervention Study
Constipation is a common problem among children. The majority of children suffering from
constipation have no underlying disease. Although constipation has no basis in underlying
disease, it often leads to a reduced quality of life of children who are on par with or
worse than for children suffering from serious diseases such as cardiovascular and rheumatic
diseases.
Despite the high frequency of constipation among children, little is known about the causes
and treatment of constipation.
Treatment consists of symptomatic treatment with various laxatives. Movicol and Movicol
junior has proven very effective and are therefore widely used in children as disimpaction
and maintenance treatment. There is currently no research to prove the need for and length
of maintenance treatment with laxative medications in children.
The purpose is to examining the effectiveness of maintenance treatment with Movicol.
Additional til study will examine how the anal diameter change during a course of treatment
and the degree to which it can be used as an indicator of treatment efficacy.
The study will test the following:
• What is the effect of maintenance treatment with PEG compared to placebo?
The results from this study are expected to form the basis for an evidence-based approach to
the use of maintenance therapy and the use of ultrasound of the rectum in children with
constipation.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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