Constipation Clinical Trial
Official title:
Modifications of the Anal Muscle Cortical Excitability Area After Biofeedback Training
Looking for a modification of the cortical excitability of the motor area corresponding to the external anal sphincter after biofeedback sessions.
Introduction: Nervous control of pelvic floor is not much known. The dysfunction of this
musculature, and particularly of the external anal sphincter, is a frequent cause of anal
incontinence and/or dyschesia. Biofeedback training is often offered to patients suffering
from incontinence or constipation. However, its mechanisms of action is still controversial.
Objective of the study: to compare excitability of the cortical area responsible for control
volunteer of the external anal sphincter in healthy subjects before and after 4 biofeedback
sessions.
Subjects and methodology: we offer to perform two groups of 12 healthy subjects (one active
and one control group) without any neurological or digestive disease and having never
performed biofeedback. In each group, cortical excitability will be evaluated by cortical
magnetic stimulation (curve intensity/amplitude, silent period, inter-stimulus period, motor
threshold) before and after 4 biofeedback sessions (one session by week) in active group or
4 placebo sessions (placebo group).
We hope to show a modification of cortical excitability in subjects performing biofeedback
compared to others.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Caregiver)
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