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Constipation clinical trials

View clinical trials related to Constipation.

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NCT ID: NCT00402337 Completed - Clinical trials for Chronic Constipation

Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation

Start date: November 2006
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to evaluate the efficacy and safety of administration of linaclotide acetate in patients with chronic constipation.

NCT ID: NCT00402038 Completed - Clinical trials for Advance Illness Patients With OIC

Study of Methylnaltrexone (MNTX) for the Relief of Constipation

Start date: February 2004
Phase: Phase 3
Study type: Interventional

To determine the efficacy of subcutaneous MNTX to relieve opioid-induced constipation in patients with advanced medical illness.

NCT ID: NCT00401362 Completed - Clinical trials for Advanced Illness Patients With Opioid Induced Constipation

A a Single Dose Efficacy Study in Inducing Laxation in Advance Illness Patients

Start date: February 2003
Phase: Phase 3
Study type: Interventional

To test the effectiveness of MNTX in advanced illness subjects.

NCT ID: NCT00399659 Terminated - Clinical trials for Opioid-induced Constipation

Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.

Start date: November 2006
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of Tegaserod in opioid-induced constipation (OIC) in patients with non-cancer pain. Patients who enter this study PRIOR to the core study (CHTF919N2201) interim analysis (IA) receive the treatment as follows: Patients on tegaserod 6 mg twice daily (b.i.d.) or 12 mg once daily (o.d.) in the core study will remain on the same dose in the extension (double-blind). Patients on placebo during the core study will receive tegaserod 12 mg o.d. (open-label) Patients who enter this study AFTER the core study interim analysis will receive the selected tegaserod dose regimen (open-label) determined by the core study IA.

NCT ID: NCT00399542 Completed - Clinical trials for Irritable Bowel Syndrome

Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation

Start date: May 2005
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to evaluate the efficacy and safety of administration of lubiprostone in patients with irritable bowel syndrome with constipation.

NCT ID: NCT00398021 Completed - Constipation Clinical Trials

Predictors of Constipation in Healthy Children

Start date: June 2006
Phase: N/A
Study type: Observational

The purpose of this research is to see if a questionnaire on bowel habits can help identify children who will have constipation 12 months later.

NCT ID: NCT00391820 Completed - Clinical trials for Chronic Constipation

Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial)

Start date: October 2006
Phase: Phase 2
Study type: Interventional

Study 0038 compares the safety and effectiveness of an investigational drug, TD-5108 with placebo (a sugar pill) for the treatment of chronic constipation.

NCT ID: NCT00380250 Completed - Clinical trials for Irritable Bowel Syndrome With Constipation

Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation

Start date: May 2005
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to evaluate the efficacy and safety of administration of lubiprostone in patients with irritable bowel syndrome with constipation.

NCT ID: NCT00368823 Completed - Constipation Clinical Trials

A Trial of Point of Care Information in Ambulatory Pediatrics

Start date: November 1999
Phase: Phase 3
Study type: Interventional

Does presentation of clinical evidence for decision making at point-of-care improve prescribing patterns in ambulatory pediatrics?

NCT ID: NCT00366431 Completed - Constipation Clinical Trials

Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain

Start date: August 2006
Phase: Phase 2
Study type: Interventional

The primary purpose of the protocol is to evaluate the safety, efficacy, and tolerability of MOA-728 in subjects with Opioid-Induced Bowel Dysfunction (OIBD) with associated chronic non-malignant pain.