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Constipation clinical trials

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NCT ID: NCT05506397 Completed - Constipation Clinical Trials

Acupressure for Constipation in the Elderly

Start date: February 24, 2021
Phase: N/A
Study type: Interventional

This study was carried out to determine the effect of acupressure applied to LI4, CV12, ST25 and ST36 acupuncture points for a total of 21 minutes, three to each point, on the symptoms of constipation and quality of life of elderly individuals.

NCT ID: NCT05473546 Completed - Critical Illness Clinical Trials

Diarrhea and Stipsis in Critically Ill Patients (NUTRITI)

NUTRITI
Start date: October 11, 2019
Phase:
Study type: Observational

This study prospectively observed the complications intended as diarrhea or sti-sis that critically ill patients developed within 7 days after ICU admission. In addition, secondary aims investigated through bioimpedenziometry the loss of lean body mass and changes in phase angle during the same period of ICU stay.

NCT ID: NCT05447481 Completed - Clinical trials for Constipation - Functional

Evaluation of the Effect of Chicory Inulin-type Fructans in Constipated Adults

Start date: November 11, 2015
Phase: N/A
Study type: Interventional

Constipation is common in the general population, especially in women and in the elderly, which can significantly affect quality of life of the individual. There is a general consumer trend to seek natural food options, also when addressing health issues such as constipation. Consumers seek tasty options and there is a paucity of tasty functional foods to address constipation. Adding natural fiber to food, like inulin-type fructans from chicory root fiber, can increase fiber intake and potentially prevent or resolve constipation issues. This study aimed to increase the body of scientific data on inulin-type fructans by way of a randomized, placebo-controlled, cross-over study. Maltodextrin was used as the placebo in this study.

NCT ID: NCT05447403 Completed - Constipation Clinical Trials

Effect of Chewing Gum and WeChat Enhanced Instructions on the Bowel Preparation Quality in Patients With Constipation

Start date: February 24, 2022
Phase: N/A
Study type: Interventional

Patients with constipation are more likely to have poor bowel preparation quality due to slow gut motility and poor emptying ability. Gum chewing, as a proxy of sham feeding, is a very simple way used to accelerate gut motility. And a previous study found that enhanced instructions by WeChat could improve bowel preparation quality. Thus, investigators conducted a single-center randomized controlled trial to explore the effect of chewing gum combined with manual enhanced instructions by WeChat on the bowel preparation quality for colonoscopy in patients with constipation.

NCT ID: NCT05437523 Completed - Clinical trials for Functional Constipation

Clinical Implementation of a Pictographic Constipation Action Plan for Children With Functional Constipation

USCAP
Start date: August 1, 2020
Phase: N/A
Study type: Interventional

Constipation is a common disorder that globally affects 0.7% to 29.6% of children. The majority of these children receive the diagnosis of functional constipation. Functional Constipation can be challenging to diagnose and treat. The ROME IV criteria provides structure in the approach to Functional Constipation by standardizing diagnosis criteria. Functional Constipation should be suspected when a child has at least two symptoms per week for the last month consisting of: two or fewer defecations in the toilet per week, greater than or equal to 1 episode of fecal incontinence per week, history of retentive posturing or excessive volitional stool retention, history of painful or hard bowel movements, presence of a large fecal mass in the rectum, or history of large diameter stools that can obstruct the toilet. Written action plans and similar self-management tools have been associated with improved clinical and patient-reported outcomes for several pediatric chronic disease processes including anaphylaxis, asthma, and atopic dermatitis. These tools have been shown to improve patient/caregiver confidence in disease self-management at home, to increase adherence to pharmacotherapy regimens, and ultimately to enhance patient-centered outcomes. The impact of a Constipation Action Plan on Functional Constipation clinical and patient-related outcomes has not been investigated. The aim of this project was to implement and to evaluate the effectiveness of the Uniformed Services Constipation Action Plan in the management of children with Functional Constipation in a pediatric gastroenterology clinic.

NCT ID: NCT05429333 Completed - Clinical trials for Constipation - Functional

Effect of Microbiome Modulation by Diet in Functional Constipation

Start date: December 14, 2020
Phase: N/A
Study type: Interventional

Current medications and behavioral modifications have limited success in the treatment of functional constipation (FC). An individualized diet based on microbiome analysis may improve symptoms in FC. In the present study, we aimed to investigate the impacts of microbiome modulation on chronic constipation. patients fulfilling Rome IV criteria for functional constipation were randomized into two groups. The Control group received sodium picosulfate plus conventional treatments (i.e., laxatives, enemas, increased fiber, and fluid intake). The study group underwent microbiome analysis and received an individualized diet with the assistance of a soft computing system (Enbiosis Biotechnology®, Sariyer, Istanbul). Differences in Patient Assessment Constipation-Quality of Life (PAC-QoL) score and complete bowel movements per week (CBMpW) were compared between groups after 6 week-intervention.

NCT ID: NCT05392439 Completed - Abdominal Pain Clinical Trials

Effect of taVNS on Abdominal Pain and Other Symptoms in Constipation-predominant Irritable Bowel Syndrome

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

This study aims to investigate the effects and possible mechanisms of transcutaneous auricular vagal nerve stimulation (taVNS) on abdominal pain and other symptoms in patients with IBS-C.

NCT ID: NCT05343910 Completed - Constipation Clinical Trials

The Effect of Aroma Massage on Constipation

aromatherapy
Start date: December 1, 2012
Phase: N/A
Study type: Interventional

Advancing age arising changes in health status and systems adversely affect the quality of life of the elderly and the elderly face many complex health problems. Constipation is one of the common problems in the elderly. Therefore, The aim of this study is to examine effects of aromatherapy massage on constipation in the elderly.

NCT ID: NCT05341180 Completed - Constipation Clinical Trials

Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial

PEGASIS
Start date: May 27, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The existing literature stresses the better efficacy of polyethylene glycol (PEG) over other stool softeners like lactulose or isabgol to improve functional constipation. But there is no consensus regarding the efficacy of PEG alone vs lactulose combined with isabgol used as stool softeners, frequently used for relieving acute constipation in an acute fissure in ano. Hence a good quality randomised study to compare both efficacies is the need of the hour.

NCT ID: NCT05336305 Completed - Clinical trials for Chronic Kidney Diseases

Polydextrose for Patients With Chronic Kidney Disease

Start date: March 30, 2021
Phase: N/A
Study type: Interventional

Constipation is a common complication in patients with chronic kidney disease (CKD), especially in hemodialysis (HD) patients. Reduced intake of fibre-rich food is among the most important causes of constipation. The study aims to investigate the possible influence of polydextrose (PDX) supplementation on constipation in patients with CKD on HD.