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Conscious Sedation clinical trials

View clinical trials related to Conscious Sedation.

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NCT ID: NCT02679781 Completed - Conscious Sedation Clinical Trials

Nasal Versus Oral Midazolam Sedation in Routine Pediatric Dental Care

Start date: March 28, 2017
Phase: N/A
Study type: Interventional

The general objective of the study is to compare the efficacy of administering midazolam orally as syrup versus nasally with nasal atomizer. The specific objectives are to measure: 1) acceptability of the medication, 2) effect on behavior, 3) time of onset, 4) maximum working time.

NCT ID: NCT02573818 Terminated - Conscious Sedation Clinical Trials

Sedasys Post Approval Study Users Response to System Alarms

Start date: September 1, 2015
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the users' responses to the SEDASYS® System alarms during esophagogastroduodenoscopy (EGD) or colonoscopy.

NCT ID: NCT02518919 Completed - Conscious Sedation Clinical Trials

Procedural Sedation And Analgesia in Children in the Emergency Department: The Role of Adjunct Therapies

Start date: October 1, 2015
Phase: N/A
Study type: Interventional

The role of Adjunct therapies such as Child Life therapy and Music listening during Procedural Sedation and Analgesia(PSA) for children during painful procedures has not been studied in the Emergency Department (ED). The investigators hypothesize that there will be a reduction in sedation medication dosage without change in sedation efficacy by addition of music therapy and Child Life to standard sedation protocol in children 3-15 years of age who undergo PSA for painful (orthopedic procedures, laceration repair, incision and drainage) procedures in a Pediatric emergency Department (PED).

NCT ID: NCT02444260 Recruiting - Anesthesia, Local Clinical Trials

A Trial of Local Anaesthesia Versus Local Anaesthesia and Conscious Sedation for Hernioplasty

Start date: December 2013
Phase: Phase 3
Study type: Interventional

The aim of this RCT is to compare patient outcomes of inguinal hernioplasty under Local Anaesthesia alone versus Local Anaesthesia and Conscious Sedation Specific study objectives are to determine the effect of conscious sedation on: (i) patient satisfaction (ii) postoperative pain (iii) time to discharge (iv) intraoperative complications (v) postoperative functional status (vi) short-term postoperative complications (vii) long-term postoperative complications

NCT ID: NCT02408302 Not yet recruiting - Children Clinical Trials

Buccal Midazolam Versus Nasal or Oral Midazolam Sedation for Minor Invasive Procedures in Children

Start date: April 2015
Phase: Phase 4
Study type: Interventional

Currently Midazolam sedation is the standard of care for minor invasive procedures in pediatric patients; its use is restricted to two routes of administration for this purpose oral and intranasal. A third route of administration (buccal) is tested and approved for seizure management. In the investigators' study the researchers investigate the buccal route of administration versus oral or intranasal administration for sedation. The investigators' hypothesis is that buccal route of administration is more convenient than intranasal and better absorbed than oral.

NCT ID: NCT01873612 Completed - Hypoxia Clinical Trials

Acute Ventilatory Response to Hypoxia During Sedation With Dexmedetomidine Compared to Propofol in Healthy Male Volunteers

Start date: May 2013
Phase: Phase 4
Study type: Interventional

The overall aim with this project is to investigate the effect of dexmedetomidine on control of breathing in healthy volunteers and to compare it with propofol at the same degree of sedation.

NCT ID: NCT01805726 Completed - Bronchoscopy Clinical Trials

Sedation During Bronchoscopy:Dexmedetomidine vs Alfentanil

Start date: February 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to find the best sedation necessary for patients undergoing bronchoscopy. Patients are randomized to three different regimes of sedation during bronchoscopy were studied: 1. - Group standard/control: local anesthesia only(C) 2. - Group alfentanil + local anesthesia(A) 3. - Group dexmedetomidine + local anesthesia(D) The primary endpoint is the bronchoscopy score. Secondary endpoints are: Level of sedation and tolerance bronchoscopy examination. Measured parameters on the safety of examination are: the lowest saturation, needs to supplemental oxygen, amnesia , choking sensation or chest pain and if the patient is ready or not to undertake bronchoscopy second time in his life if necessary. Endtidal CO2, Respiratory rate, Blood pressure, Heart rate, level of oxygen are collected every 5 minutes before, during and after the bronchoscopy.

NCT ID: NCT01778608 Completed - Conscious Sedation Clinical Trials

Feasability Test of a Handset Device to Detect Levels of Sedation and Loss of Consciousness

Start date: January 2012
Phase:
Study type: Observational

Sedation is often administered to relieve anxiety and discomfort during uncomfortable procedures in elderly patients. Patient control of sedation offers many potential benefits for patients and healthcare professionals, including improved safety and patient satisfaction. The investigators overall goal is to develop a patient controlled intravenous sedation system that is effective but very safe for the patient, and requires minimal supervision by a doctor or nurse. To fulfill these criteria, a sedation system should incorporate fail-safe safety mechanisms. A key safety-critical component is a method of objectively assessing the degree of sedation of the patient, and of preventing him from self-administering unsafe doses of the sedative drug. The investigators have designed a new sedation system that uses a measure of the speed of response of the patient to a defined non-noxious stimulus to determine whether or not it is safe to allow him to self-administer further levels of sedation. Before being able to execute a volunteer study in order to determine a rational selection of optimal threshold response time, a feasibility test on the handset device is required.

NCT ID: NCT01287572 Not yet recruiting - Conscious Sedation Clinical Trials

Efficiency of Ventilation During Conscious Sedation in the Pediatric Intensive Care Unit

Start date: February 2011
Phase: N/A
Study type: Observational

Pediatric patients admitted to the intensive care unit and requiring conscious sedation for minor surgical procedures are at risk to hypoventilate and retain CO2. The rise in CO2 levels is not well described and unpredicted. In this study the investigators will monitor CO2 levels transcutaneously using SDMS (SenTec digital Monitoring System) a device recently approved for clinical use. The hypothesis is ventilation of patients undergoing conscious sedation is compromised and CO2 levels might rise significantly to levels that potentially can effect hemodynamics. In order to avoid hemodynamic changes proper and routine monitoring is recommended.

NCT ID: NCT01143766 Completed - Conscious Sedation Clinical Trials

Gabapentin to Improve Patient Tolerance in Endoscopic Retrograde Cholangiopancreatography (ERCP)

Start date: April 2010
Phase: N/A
Study type: Interventional

The standard approach to sedation in endoscopic retrograde cholangiopancreatography (ERCP) involves the use of benzodiazepines and opiates to achieve a moderate depth of sedation. There is data to suggest supplementing this regimen with gabapentin may lead to reduced pain, higher patient satisfaction and lower opiate requirements. The investigators are conducting a clinical trial to study this hypothesis.