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Conjunctivitis, Allergic clinical trials

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NCT ID: NCT02271009 Completed - Clinical trials for Allergic Rhino-Conjunctivitis

Compare Dose Regimens of AllerT, in Adults With Allergic Rhino-Conjunctivitis to Birch Pollen Studied in EEC

Start date: October 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find the optimal dose of AllerT that should be used to treat moderate to severe allergies due to birch tree pollen. There are 4 treatment groups in this study; 3 treatment groups will receive AllerT at different doses and 1 treatment group will receive placebo. This study will also assess the effectiveness and safety of AllerT compared to placebo in relieving allergy symptoms.

NCT ID: NCT02251613 Completed - Clinical trials for Allergic Conjunctivitis

Effectiveness of Olopatadine HCl Ophthalmic Solution for the Treatment of Allergic Conjunctivitis in Japan

Start date: December 2013
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of Olopatadine Hydrochloride (HCl) ophthalmic solution 0.1% versus Epinastine HCl ophthalmic solution, 0.05% in a population of healthy, adult Japanese patients (20 years of age or older) with a history of allergic conjunctivitis to Japanese Cedar Pollen. Patients will be randomly assigned to receive Olopatadine HCl ophthalmic solution, 0.1% in one eye and Epinastine HCl ophthalmic solution, 0.05% in the fellow eye, after which a conjunctival allergy challenge (CAC) with Japanese cedar pollen will be performed.

NCT ID: NCT02245360 Completed - Clinical trials for Seasonal Allergic Rhinitis

Study Immunology and Safety of 60-day Treatment of SQ Grass SLIT (Sublingual Immunotherapy)-Tablet in Adult Subjects With Grass Pollen-induced Allergic Rhinoconjunctivitis

Start date: October 2014
Phase: Phase 3
Study type: Interventional

To investigate the immunologic effects and safety of 60-day treatment of the Standardized Quality units (SQ) grass Sublingual immunotherapy (SLIT)-tablet in adult subjects with grass pollen-induced allergic rhinoconjunctivitis in a double-blind, placebo-controlled study.

NCT ID: NCT02166268 Completed - Clinical trials for Grass Pollen Induced Allergic Rhinoconjunctivitis

Evaluation of the Efficacy and Safety of AVANZ® Phleum Pratense in Grass Pollen-induced Allergic Rhinitis During Controlled Exposure in an Environmental Challenge Chamber

AV-G-03
Start date: June 2014
Phase: Phase 2
Study type: Interventional

The clinical trial will investigate the efficacy of Avanz Phleum pratense in the treatment of rhinitis in an environmental challenge chamber.

NCT ID: NCT02161146 Completed - Clinical trials for Conjunctivitis, Allergic

AGN-229666 Ophthalmic Solution in Japanese Patients With Allergic Conjunctivitis

Start date: June 4, 2014
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of AGN-229666 for the prevention of allergen-mediated conjunctivitis.

NCT ID: NCT02148744 Completed - Atopic Dermatitis Clinical Trials

Safety and Tolerability of XmAb®7195 in Adult Healthy Volunteers and Adult Subjects With a History of Allergic Rhinitis and/or Allergic Conjunctivitis and/or Atopic Dermatitis

Start date: May 2014
Phase: Phase 1
Study type: Interventional

This first-in-human (FIH) study is a randomized, double-blinded, placebo-controlled, ascending dose study to investigate the safety, tolerability, and pharmacokinetics of XmAb7195 in adult healthy volunteers and in adult subjects with elevated IgE levels.

NCT ID: NCT02132169 Completed - Clinical trials for Atopic Disease (Including Allergic Conjunctivitis)

A Multi-Center Study Evaluating the Safety of AC-170 0.24%

Start date: May 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety of AC-170 0.24% used twice daily in Healthy Adult Subjects and in Pediatric subjects with a history or family history of atopic disease (including allergic conjunctivitis).

NCT ID: NCT02131051 Completed - Clinical trials for Allergic Rhinoconjunctivitis

Application of Ectoine Containing Nasal Spray and Eye Drops in Patients With Allergic Rhinitis

Start date: June 2010
Phase: N/A
Study type: Observational

This is a comparative, open label, parallel group, non interventional study to further demonstrate the effectiveness and tolerability of Ectoin Allergy Nasal Spray and Eye drops. In addition the effectiveness and safety shall be compared to Azelastine containing nasal Sprays and Eye drops. The patient applied Ectoin® Rhinitis Nasal Spray / Eye drops or takes Azelastine nasals spray and eye drops according to the instructions for use. The observation takes place over a period of 7 days. Response to treatment is recorded at day 7 by the physician and in daily by the patient in a dairy.

NCT ID: NCT02082899 Completed - Clinical trials for Allergic Conjunctivitis

A Single Center Study for the Treatment of Moderate to Severe Allergic Conjunctivitis (EBI-005-AC-1)

Start date: February 2014
Phase: Phase 2
Study type: Interventional

This is a Phase II Single Center, Randomized, Double-Masked, Vehicle-Controlled, Parallel, Group Study to Assess the Efficacy of EBI-005 Topical Ophthalmic Solution for the Treatment of Moderate to Severe Allergic Conjunctivitis Using an Environmental Exposure Chamber (EEC) Model and Conjunctival Allergen Provocation Test (CAPT) Model. Approximately 150 subjects will be enrolled and randomized in one study center in Canada for a duration of 0.33 years.

NCT ID: NCT02082262 Completed - Clinical trials for Conjunctivitis, Allergic

AGN-229666 Ophthalmic Solution for the Treatment of Seasonal or Perennial Allergic Conjunctivitis

Start date: March 2014
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of AGN-229666 for the treatment of seasonal or perennial allergic conjunctivitis.