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Conjunctivitis, Allergic clinical trials

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NCT ID: NCT00884585 Completed - Clinical trials for Atopic Conjunctivitis

Efficacy and Safety Study of Cyclosporine 0.010% to Treat Atopic Keratoconjunctivitis

Start date: May 2009
Phase: Phase 3
Study type: Interventional

This study evaluates the efficacy and safety of Cyclosporine 0.010% eye drops in the treatment of Atopic Keratoconjunctivitis (chronic and severe inflammation of the eye). The study consists of a double-masked phase, and open-labeled phase, and an open-labeled maintenance phase. For the first 3 months of the study, patients will receive either masked Cyclosporine 0.010% eye drops or vehicle four times daily; for the next 6 months, patients may receive open-labeled Cyclosporine 0.010% eye drops four times daily. At month 9, patients who are in remission, will be re-randomized to receive either open-labeled Cyclosporine 0.010% eye drops four times daily or twice daily.

NCT ID: NCT00882687 Completed - Clinical trials for Allergic Conjunctivitis

Efficacy Study to Evaluate the Effectiveness of 3 Concentrations of SAR 1118 in Allergic Conjunctivitis

Start date: April 24, 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether SAR 1118 at three different concentrations, compared to placebo, is effective in the prevention of the signs and symptoms of allergic conjunctivitis

NCT ID: NCT00881673 Withdrawn - Clinical trials for Allergic Conjunctivitis

To Evaluate the Efficacy of AL-38583 in the Reduction of Tear Eosinophil Count Following Conjunctival Allergen Challenge

Start date: May 2009
Phase: Phase 2
Study type: Interventional

The purpose of the study is to determine whether Al38583 Ophthalmic Solution is safe and effective in reducing tear eosinophil levels at 5-8 hours after Conjunctival Allergen Challenge (CAC).

NCT ID: NCT00841516 Completed - Clinical trials for Allergic Rhinoconjunctivitis

Immunological and Histological Evaluation of Specific Immunotherapy With Recombinant Hypoallergenic Derivative

Start date: December 2007
Phase: Phase 2
Study type: Interventional

This trial is performed for the immunological and histological evaluation of specific immunotherapy with an aluminium hydroxide-adsorbed recombinant hypoallergenic derivative of the major birch pollen allergen, rBet v1-FV

NCT ID: NCT00841256 Completed - Clinical trials for Allergic Rhinoconjunctivitis

Multicenter Trial of Sublingual Immunotherapy With a Solution of Grass Pollen Allergen Extract in Children

Start date: February 2008
Phase: Phase 3
Study type: Interventional

Evaluation of safety and efficacy of sublingual immunotherapy with grass pollen allergens formulated as solution in comparison to a symptomatic standard treatment with add on placebo in grass pollen allergic children suffering from allergic rhinitis/rhinoconjunctivitis with or without bronchial asthma.

NCT ID: NCT00836485 Completed - Clinical trials for Allergic Conjunctivitis

Evaluation of the Safety and Efficacy of Ketotifen 4.0% Patch as Compared to Placebo Patch, Olopatadine 0.2% Ophthalmic Solution, and Artificial Tears in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis

Start date: February 2009
Phase: Phase 2
Study type: Interventional

This is a phase 2 study that will consist of 4 visits over a 5 week period. Drug will be evaluated using the conjunctival allergen challenge model of allergic conjunctivitis.

NCT ID: NCT00833495 Completed - Clinical trials for Allergic Conjunctivitis

Evaluation of Efficacy of Coadministration of FOV1101-00 and Prednisolone Acetate in Patients With Mild Ongoing Ocular Allergic Inflammation

Start date: January 2009
Phase: Phase 2
Study type: Interventional

This is a phase 2 study that will consist of 3 visits during a 3 week period conducted at up to 5 sites. The purpose of this study is to determine how effective the combination of Pred Mild® and FOV1101-00 is compared to either Pred Forte® alone or to vehicle alone in the prevention of eye allergies. Study subjects will be randomized to one of the following: - FOV1101-00 concentration 1 and Pred Mild® - FOV1101-00 concentration 2 and Pred Mild® - Vehicle of FOV1101-00 and Pred Forte® - Vehicle of FOV1101-00 and Vehicle of FOV1101-00

NCT ID: NCT00833066 Completed - Clinical trials for Seasonal Allergic Rhinoconjunctivitis

Safety Study of Grass Pollen-derived Peptides to Treat Seasonal Allergic Rhinoconjunctivitis

Start date: February 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether the oral administration of grass pollen peptides is safe and effective in the treatment of allergic rhinitis.

NCT ID: NCT00824447 Completed - Clinical trials for Allergic Rhinoconjunctivitis

Long-term Efficacy and Safety Study With Oralgen Grass Pollen

Start date: August 2007
Phase: Phase 2/Phase 3
Study type: Interventional

This study is designed to give additional information on the efficacy, safety and local effects (tolerability) of a dose of sublingual immunotherapy administered once a day, during a second grass pollen season.

NCT ID: NCT00818805 Completed - Clinical trials for Allergic Conjunctivitis

Efficacy Investigation Study of Olopatadine Hydrochloride Ophthalmic Solution Using OHIO Chamber in Patients With Seasonal Allergic Rhinitis (SAR)

Start date: July 2008
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy of olopatadine 0.1% using the OHIO Chamber in patients with seasonal allergic conjunctivitis.