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Conjunctivitis, Allergic clinical trials

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NCT ID: NCT05668390 Active, not recruiting - Clinical trials for Allergic Rhinoconjunctivitis

Safety and Efficacy of STALORAL® Birch 300 IR in a Paediatric Population With Birch Pollen-induced ARC w/o Asthma

YOBI
Start date: November 14, 2023
Phase: Phase 3
Study type: Interventional

Allergic rhinoconjunctivitis due to birch pollen is a seasonal problem which manifests as a combination of nasal symptoms (such as congestion, runny nose, sneezing, itching of the nose) and ocular symptoms (such as red, itchy and watery eyes). For several birch-allergic patients, allergic rhinoconjunctivitis occurs with an oral allergy syndrome. The purpose of this study is to demonstrate the safety and efficacy of the study drug (STALORAL Birch 300 IR) in children and adolescents with birch pollen-induced allergic rhinoconjunctivitis, with or without asthma, when treated before and during the pollen season. Approximately 699 children will participate in this study. The study will be conducted worldwide in approximately 100 medical sites in about 14 countries. The total duration of the study will be approximately 20 months.

NCT ID: NCT05591755 Completed - Clinical trials for Seasonal Allergic Conjunctivitis

Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination in Adults With Seasonal Allergic Conjunctivitis

Start date: November 18, 2022
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy of Combo compared to its individual components and compared to vehicle in a population of subjects with seasonal allergic conjunctivitis.

NCT ID: NCT05579730 Completed - Clinical trials for Allergic Conjunctivitis

Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination for the Treatment of Allergic Conjunctivitis

Start date: November 18, 2022
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy of Combo (Drug Product Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Ophthalmic Solution) compared to its individual components and vehicle in a population of subjects with allergic conjunctivitis:

NCT ID: NCT05353101 Completed - Clinical trials for Vernal Keratoconjunctivitis

Cyclosporine 0.05% Eye Drops for Vernal Keratoconjunctivitis Trial

Start date: July 1, 2020
Phase: Phase 1
Study type: Interventional

To observe and compare the clinical efficacy of cyclosporine 0.05% eye drops with Loteprednol Etabonate 0.5% and Tobramycin Eye Drops 0.3% in the treatment of Vernal Keratoconjunctivitis in developing regions of China.

NCT ID: NCT05314621 Completed - Clinical trials for Allergic Conjunctivitis

A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Flonase® Allergy Relief in Subjects With Allergic Conjunctivitis

Start date: December 31, 2021
Phase: Phase 4
Study type: Interventional

This is a single-center, randomized, double-masked, parallel study.

NCT ID: NCT05265910 Completed - Clinical trials for Allergic Conjunctivitis

A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Claritin® Tablets 24-Hour in Subjects With Allergic Conjunctivitis

Start date: December 14, 2021
Phase: Phase 4
Study type: Interventional

This is a single-center, randomized, double-masked, parallel study. In this clinical study, the efficacy comparison between Pataday® Once Daily Relief Extra Strength and Claritin® Tablets 24-Hour will be made using the Ora-CAC model, a validated clinical model accepted by regulatory agents for assessing the efficacy of products on the signs and symptoms of allergic conjunctivitis.

NCT ID: NCT05234554 Completed - Clinical trials for Allergic Conjunctivitis

The INVIGORATE 2 Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis

Start date: January 21, 2022
Phase: Phase 3
Study type: Interventional

The INVIGORATE 2 Trial: A single-center, randomized, double-masked, crossover design, vehicle-controlled, Phase 3 clinical trial to assess the efficacy and safety of reproxalap ophthalmic solution (0.25%) compared to vehicle in subjects with seasonal allergic conjunctivitis using the environmental exposure chamber (EEC).

NCT ID: NCT05191186 Active, not recruiting - Allergic Asthma Clinical Trials

Documentation of Efficacy of Intralymphatic Allergen Immunotherapy

ILITNU
Start date: February 1, 2020
Phase: Phase 3
Study type: Interventional

Investigation of the clinical efficacy of 3 intralymphatic injections with grass pollen extract into inguinal lymph nodes on combined symptom-medication scores during grass pollen season in grass pollen allergic patients compared to placebo

NCT ID: NCT05186025 Active, not recruiting - Clinical trials for Allergic Conjunctivitis

Tyrosine Allergoid Paediatric and Adult Study

Start date: November 6, 2020
Phase:
Study type: Observational

The primary objective of this 5-year study is to demonstrate non-inferiority of children compared to adults by exploring long-term effectiveness after treatment with TA Bäume (trees) and TA Gräser (grass) following a perennial posology.

NCT ID: NCT05076084 Completed - Clinical trials for Vernal Keratoconjunctivitis

Evaluation of the Efficacy and Safety of Tacrolimus Drops in Children With Vernal Keratoconjunctivitis

KERAVER
Start date: October 19, 2021
Phase:
Study type: Observational

Non-interventional single-center cohort study (Rothschild Foundation Hospital) of patients aged 0 to 18 years followed up in ophthalmology for KCV, treated with tacrolimus 0.1% eye drops previously treated with ciclosporin 2% with treatment failure. 1. Prospective collection of quality of life from the parents and/or, if possible, the children via the QUICK questionnaire and 6 additional questions 2. Retrospective collection of clinical data (secondary endpoints) from the patients' medical records, aiming to compare the period before the start of treatment and the period under treatment with TALYMUS The objective of this study is to evaluate the response to TALYMUS® treatment in patients with Vernal keratoconjunctivitis who have failed ciclosporin 2% therapy, whether due to lack of efficacy, compliance difficulties or poor tolerance.