Pregnancy Outcomes in Congenital Myasthenie Syndrome

Congenital Myasthenic Syndrome Clinical Trial

— POCoMS  

Official title:

Retrospective Study :Describe the Changes of the Disease in Many Cases Likely to Aggravate.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01474980
• Other study ID #: 2010-A00495-34
• Status: Completed
• Phase: N/A
• First received: November 16, 2011
• Last updated: November 17, 2011
• Start date: January 2010
• Est. completion date: October 2011

Study information

• Verified date: November 2011
• Source: Institut de Myologie, France
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
• Study type: Observational

Clinical Trial Summary

This is a retrospective study that follows the clinical evolution, the pregnancy and the post-partum perioad of female patients with Congenital Myasthenic Syndrome.

Description:

The aim of this study is to better understand the action of hormonal factors that are presumably incriminated for the fluctuation of the disease. The investigators would also like to better adress the issues of women with Congenital Myasthenic Syndrome, who desire a pregnancy : the possibility of decompensation, the problems that can arise during the course of the childbearing, the risk of foetal malformations.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: October 2011
• Est. primary completion date: January 2011
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years and older

Eligibility

Inclusion criteria:

• Adult women

• Congenital myastenic syndrome genetically confirmed or with clinical compatible and electrophysiological evidence

• Written consent

Exclusion Criteria:

• Neurological or general pathology occurs significantly with the initiation and conduct of a pregnancy.

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Congenital Myasthenic Syndrome
• Lambert-Eaton Myasthenic Syndrome
• Myasthenic Syndromes, Congenital

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Institut de Myologie, France	Assistance Publique - Hôpitaux de Paris