Bosentan Therapy in Children With Functional Single Ventricle

Status Completed

Clinical Trial Summary

Bosentan is a kind of dual endothelin receptor antagonist.The purpose of this study is to investigate if Bosentan therapy can modify the outcome of children with functional single ventricle.

Clinical Trial Description

Increased pulmonary vascular resistance (PVR) is a serous issues in children with functional single ventricle during the staged operative period. The purpose of this study is to investigate if Bosentan therapy can improve the survival and life quality after staged Fontan procedure in the children with high risk of increased PVR. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01662037
Study type	Interventional
Source	Shanghai Jiao Tong University School of Medicine
Contact
Status	Completed
Phase	Phase 2
Start date	January 2010
Completion date	June 2012

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