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Initiation of Resuscitation While Attached to the Cord With Congenital Diaphragmatic Hernia — INSPIRE-CDH  

Congenital Diaphragmatic Hernia Clinical Trial

Official title:
Initiation of Resuscitative Care While on Placental Circulation for Infants With Congenital Diaphragmatic Hernia - a Randomized Pilot Trial

Clinical Trial Summary

This study aims to measure the cardio-respiratory physiological consequences of initiating resuscitation during placental transfusion (PT) with an intact umbilical cord in infants with congenital diaphragmatic hernia (CDH). PT, mainly via delayed cord clamping, has been shown to offer a higher circulating blood volume, less need for blood transfusion, less need for inotropes in infants.

Currently infants with CDH receive immediate cord clamping (ICC) to facilitate immediate resuscitation including immediate intubation and mechanical ventilation.

With the development of a resuscitation platform (iNSPiRE), resuscitative care can now be commenced from birth in infants with CDH to benefit from PT.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03094039
Study type Interventional
Source University of Alberta
Contact
Status Withdrawn
Phase N/A
Start date April 27, 2017
Completion date August 31, 2019
View Details
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