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Congenital Cardiac Disorders clinical trials

View clinical trials related to Congenital Cardiac Disorders.

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NCT ID: NCT05637424 Completed - Acute Kidney Injury Clinical Trials

Urine Biomarkers to Predict Acute Kidney Injury After Pediatric Cardiac Surgery

Start date: May 1, 2012
Phase:
Study type: Observational

The goal of this prospective cohort study is to evaluate, in pediatric patients after cardiac surgery, the predicting capability of biomarkers for acute kidney injury. The main questions it aims to answer: - The predicting capability of acute kidney injury (AKI) biomarkers for the primary endpoint: the occurrence of AKI stage ≥ 1 within 48-h after intensive care unit (ICU) admission. - The predicting capability of AKI biomarkers for the secondary endpoint: the occurrence of AKI stage ≥ 2 within 12-h after ICU admission. - Investigated biomarkers include urine chitinase 3-like protein 1 (uCHI3L1), urine neutrophil gelatinase-associated lipocalin (uNGAL), tissue inhibitor of metalloproteinases-2 (TIMP-2), insulin-like growth factor-binding protein 7(IGFBP7), NephroCheck® and Δ serum creatinine [postop-preop]. Differences in concentration between patients with and without AKI development were investigated, as well as AKI diagnostic performance of (combined) biomarkers. During and after cardiac surgery several blood and urine samples will be taken of participants to investigated AKI occurrence and to measure biomarker concentrations.

NCT ID: NCT03146143 Completed - Clinical trials for Congenital Cardiac Disorders

Ultrafiltration Effect on Extravascular Lung Water in Pediatric Cardiac Surgery

Start date: May 15, 2017
Phase: N/A
Study type: Interventional

study will assess the effect the ultrafiltration after pediatric congenital heart surgery on cardiopulmonary bypass. patients will be divided into two groups. first group will receive ultrafiltration and the second group will be control group without filtration. we will assess extravascular lung water by lung ultrasound, arterial oxygen tension and duration of ventilation.