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Condylomata Acuminata clinical trials

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NCT ID: NCT01796821 Completed - Genital Warts Clinical Trials

Efficacy and Safety Profiles of SR-T100 Gel on External Genital Warts/Condyloma Acuminate(EGWs)

Start date: August 2014
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy of SR-T100 gel by observing total clearance rate of treated baseline EGW(s) on the treated area.

NCT ID: NCT01676792 Completed - Genital Warts Clinical Trials

SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous Condyloma

Start date: April 2011
Phase: Phase 0
Study type: Interventional

This pilot clinical study is to evaluate the efficacy & safety of SR-T100 gel (2.3% of SM in Solanum undatum plant extract) in patients with VIN(s) or EGW(s).

NCT ID: NCT01651949 Completed - Anal Cancer Clinical Trials

Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003)

Start date: October 29, 2012
Phase: Phase 3
Study type: Interventional

This study is designed to evaluate the immunogenicity and tolerability of 9vHPV (9-valent HPV vaccine, V503) in 16- to 26-year old men and women. The overall goal is to bridge 9vHPV efficacy findings in young women to young men based on the demonstration of similar immunogenicity and safety profiles. The primary hypothesis is that 9vHPV induces antibody responses at 4 weeks postdose 3 in heterosexual males that are non-inferior to antibody responses in young women.

NCT ID: NCT01598779 Completed - Clinical trials for Condylomata Acuminata

Human Papillomavirus (HPV) Types Present in External Genital Warts (EGW) in the Argentinean Population

Start date: June 2012
Phase: N/A
Study type: Observational

The summary of this study is to know which HPV types are present in genital warts in Argentinean population.

NCT ID: NCT01532102 Completed - Clinical trials for Human Papillomavirus Infection

Safety and Efficacy Study of Topical AP611074 Gel to Treat Genital Warts

Start date: February 28, 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the safety, tolerability and efficacy of the topical application of AP611074 5% gel during 6 weeks on ano-genital warts caused by human papillomavirus (HPV).

NCT ID: NCT01520194 Not yet recruiting - Clinical trials for Female Genital Warts

The Psychosocial and Economic Burden of Genital Warts

GWburden
Start date: January 2012
Phase: N/A
Study type: Observational

Considering the importance of HPV(human papilomavirus) and related diseases in Brazil, and the lack of studies about both the economic and the psychosocial burden of these diseases, BEMFAM, a Brazilian non-governmental organization that provides reproductive health services and technical support to local governments proposes a study to measure the psychosocial and economic burden of genital warts.

NCT ID: NCT01490008 Completed - Anogenital Warts Clinical Trials

Systemic Exposure of Catechins From Veregen 15% Ointment in Patients With External Anogenital Warts and From Oral Intake of Green Tea Beverage in Healthy Volunteers

Start date: December 2011
Phase: Phase 1
Study type: Interventional

Investigation of systemic catechin exposure following topically administered Veregen® 15% ointment in patients with external genital and perianal warts and following oral intake of a standardized green tea beverage in healthy subjects. Pharmacokinetic parameters for the main catechin EGCg used as a marker of overall catechin exposure following dermal administration in the patient group will only be calculated if sufficiently consistent data can be obtained e.g. sufficient plasma catechin concentrations to pharmacokinetically evaluate plasma profiles for plasma catechin concentrations. If applicable, a safety margin for ointment use might need to be established with respect to intolerable systemic exposures of catechins following application of Veregen® ointment. In treatment arm 1, patients with anogenital warts will apply Veregen® 15% ointment 250 mg three times daily: in the morning, at midday, and in the evening on the defined anogenital administration area (total dose of 750 mg/d) for one week . In treatment arm 2, healthy subjects will ingest 500 mL commercially available green tea beverage ("Lipton® Green Limone" distributed by PepsiCo Deutschland GmbH, Neu-Isenburg, Germany), three times daily in the morning, at midday, and in the evening (total dose of 1500 mL/d) for one week. Plasma samples will be collected to aim for a complete pharmacokinetic assessment (over 24 hours) on Days 1 and 2 at Visit 2 and on Days 7 and 8 at Visit 3 (one week after first dosing). To avoid any influence on overall systemic catechin exposure deriving from any other source than Veregen® or Lipton Green Tea, all subjects participating in the trial (patients and healthy volunteers) will be asked to follow a defined diet abstaining from food or beverages known to containing catechins (a list of all prohibited and allowed foods and beverages will be provided to all subjects). For concomitant medication, only paracetamol and oral contraceptives are allowed.

NCT ID: NCT01483794 Not yet recruiting - Clinical trials for Condylomata Acuminata

Epidemiology, Costs and Psychosocial Consequences of Genital Warts in Valparaiso, Chile

Start date: November 2011
Phase: N/A
Study type: Observational

This is an observational study looking at the characteristics of patients consulting for genital warts in the first semester 2010 at the public sexual health clinic of Valparaiso, Chile. The objectives are: to have an epidemiological profile, estimating cost of the disease for the health system and the patient and analyzing possible psychosocial consequences of the condition for the patients.

NCT ID: NCT01468636 Terminated - HPV Clinical Trials

A RTC to Examine the Effectiveness of 400 mg of Oral Zinc Gluconate as Adjunctive Therapy for Ano-genital Warts

Start date: November 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to examine the effect of 400 mg of oral zinc gluconate on genital warts. Our hypothesis is that there will be a 10% difference in complete clearance of genital warts in the group randomized to oral plus standard of care compared to those randomized to placebo plus standard of care.

NCT ID: NCT01192282 Completed - Clinical trials for Human Papilloma Virus

Typing of Human Papilloma Virus (HPV) From Female Genital Warts

Start date: April 2010
Phase: N/A
Study type: Observational

This is a longitudinal observational study of women presenting to Groote Schuur Hospital with genital warts. The study will evaluate the socio-demographic characteristics of the women using a structured questionnaire. It will also document the site and extend of the genital warts and genotyping will be performed on the warts. HIV status will be determined with patient consent, treatment modalities will be documented as will the outcome of treatment over a 6 month's period. Risk factors for recurrence or failure of treatment will be analysed as will the costs of treating women with genital warts.