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Condylomata Acuminata clinical trials

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NCT ID: NCT00674739 Completed - Genital Warts Clinical Trials

Safety and Effectiveness Study of Imiquimod Creams in the Treatment of External Genital Warts

Start date: May 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether imiquimod creams are effective in treating external genital warts (EGW). The secondary objective of this study is to provide information on recurrence of EGW. Additionally the study will also look at any adverse events associated with the use of the creams. External genital and perianal warts are caused by the infection of human papillomavirus or HPV. HPV infection is a sexually transmitted disease (STD). External genital warts look like small flesh-colored, pink, or red growths on or around the external skin of sex organs or perianal area. The warts may look similar to the small parts of a cauliflower or they may be very tiny and difficult to see. They often appear in clusters of three or four, and may grow and spread rapidly. They usually are not painful, although they may cause mild pain, bleeding, and itching.

NCT ID: NCT00543543 Completed - Cervical Cancer Clinical Trials

Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001)

Start date: September 24, 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety, efficacy, and immunogenicity of V503 in comparison to GARDASIL. The primary hypotheses tested in the study were 1) V503 administered to 16- to 26-year-old adolescents and young women is generally well-tolerated, 2) V503 reduces combined incidence of Human Papillomavirus (HPV) Type 31/33/45/52/58-related disease compared with GARDASIL, and 3) V503 induces non-inferior geometric mean titers for HPV Type 6/11/16/18 antibodies compared with GARDASIL.

NCT ID: NCT00517309 Completed - Cervical Cancer Clinical Trials

Study to Test the Safety of HPV Vaccine in Women (V501-011)(COMPLETED)

FUTURE
Start date: December 28, 2001
Phase: Phase 3
Study type: Interventional

The primary purpose of the study is to test the safety of HPV Vaccine in Women

NCT ID: NCT00499967 Completed - Genital Warts Clinical Trials

Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts

Start date: August 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, tolerability and activity of GS-9191 ointment in the treatment of genital warts. GS-9191 ointment is intended for topical application directly to genital warts on the skin.

NCT ID: NCT00449982 Completed - Clinical trials for Condylomata Acuminata

Efficacy and Safety Study of Polyphenon E to Treat External Genital Warts

Start date: July 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the clinical efficacy, safety and tolerability of a Polyphenon E Ointment 10% and a Polyphenon E Ointment 15% in the treatment of external genitial warts in male and female patients.

NCT ID: NCT00189293 Completed - Genital Warts Clinical Trials

Study of Imiquimod Cream Prior to Ablative Therapy in External Ano-Genital Warts

Start date: June 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the recurrence rate following total clearance of external genital warts (EGWs) when clearance has been obtained by imiquimod (3 applications per week for 4 weeks) followed by ablative therapy (laser or electrocautery therapy) with that from just ablative therapy treatment alone.

NCT ID: NCT00092482 Completed - Cervical Cancer Clinical Trials

Immunogenicity Bridge Between an Investigational Monovalent Vaccine and the Equivalent Component of Gardasil (V501) a Quadrivalent Vaccine (V501-012)(COMPLETED)

Start date: June 28, 2002
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if an investigational vaccine with a single component develops an immune response that is similar to the equivalent investigational vaccine with four components to reduce cervical disease.

NCT ID: NCT00090285 Completed - Clinical trials for Condylomata Acuminata

An Investigational Study of Gardasil™ (qHPV Vaccine) in Reducing the Incidence of Anogenital Warts in Young Men (V501-020)

Start date: September 3, 2004
Phase: Phase 3
Study type: Interventional

This study was conducted to demonstrate that Gardasil™ (quadrivalent human papillomavirus [qHPV] vaccine) 1) is well tolerated in young men, 2) reduces incidence of external genital lesions in young men, 3) reduces the incidence of anal intraepithelial neoplasia (AIN) or anal cancer in men having sex with men (MSM), and 4) reduces incidence of Human Papillomavirus (HPV) infection in young men. In the 7-month Base Study participants received randomly assigned qHPV vaccine or placebo at Day 1, Month 2, and Month 6. Base Study follow-up continued through Month 36. In Extension 1 (EXT1), participants who received placebo or an incomplete qHPV vaccine regimen in the Base Study were offered qHPV vaccine. Participants were followed in EXT1 for 7 months. In Extension 2 [LTFU (EXT2)], long-term effectiveness, immunogenicity, and safety of qHPV vaccine were followed up to 10 years following study enrollment. Participants who received ≥1 dose of qHPV vaccine in the Base Study or EXT1 were eligible to enroll in LTFU (EXT2).