Clinical Trials Logo

Clinical Trial Summary

The implantation of a pacemaker and conventional cardiac pacing from the right ventricle (apex or septum) is an effective and safe therapy for the treatment of patients with atrioventricular block and bradycardia.


Clinical Trial Description

Pacemaker implantation and conventional cardiac stimulation from the right ventricle is an effective and safe therapy for the treatment of patients with atrioventricular block and bradycardia. But it can cause worsening of heart function, with a significant drop in LV ejection fraction, known as pacemaker-induced cardiomyopathy (PICM). Conduction system pacing (either by his or left bundle branch pacing) causes a physiological left ventricular activation through the normal conduction system thus correcting the electrical and mechanical asynchrony caused by conventional pacing. Conduction system pacing may prevent the appareance of PICM. Clinical, electrocardiographic, echocardiographic follow-up will be performed for 1 year. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05214365
Study type Interventional
Source Hospital Clinic of Barcelona
Contact Lluís Mont, MD, PhD
Phone +34 93 2271778
Email [email protected]
Status Recruiting
Phase N/A
Start date February 1, 2022
Completion date June 1, 2024

See also
  Status Clinical Trial Phase
Recruiting NCT04595487 - LVSP vs RVP in Patients With AV Conduction Disorders N/A
Recruiting NCT05187611 - Conduction System Pacing vs Biventricular Resynchronization Therapy in Systolic Dysfunction and Wide QRS: CONSYST-CRT. N/A