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Concussion clinical trials

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NCT ID: NCT01112761 Terminated - Concussion Clinical Trials

Cortical Plasticity Assessment in Athletes With a History of Concussion

Start date: April 2010
Phase: N/A
Study type: Interventional

The purpose of this research is to determine whether athletes with concussion have changes in cortical excitability. Single and paired transcranial magnetic stimulation (TMS) can be used as reliable neurophysiological marker of motor cortex reorganization in athletes with concussions. This study also aims to determine whether modulation of cortical activity by a powerful technique of noninvasive brain stimulation (tDCS) results in a different cortical response as compared with sham tDCS.

NCT ID: NCT01101724 Completed - Clinical trials for Mild Traumatic Brain Injury

Effect of Early Rest on Recovery From Pediatric Concussion

Start date: April 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to find out if strict rest for 5 days helps children get better after concussion.

NCT ID: NCT00715949 Completed - Clinical trials for Mild Traumatic Brain Injury

Neurocognitive Evaluation of Mild Traumatic Brain Injury in the Hospitalized Pediatric Population

Start date: December 2005
Phase: N/A
Study type: Observational

Brain injuries from trauma are common in children, often resulting in death and disability. Most brain injuries are minor, yet their treatment can be challenging. Because there are many different scales used to characterize the severity of brain injury, there is no consensus regarding how to manage patients with minor brain injuries. Specifically, there is no agreement on recommendations regarding the safety of return to activities following injury. In young athletes with minor brain injuries (i.e. concussions) there is strong data suggesting that return to baseline neurologic function is often delayed by days or weeks. Children allowed to return to activities too soon may be at a higher risk for a second concussion, may delay recovery or, in rare cases, die. Researchers have designed a computer-based testing system (ImPACT©) to objectively test for neurologic deficits following injury. This test has been used primarily in athletes following a concussion but is also applicable to children with brain injuries from non-sports related traumas. We propose to utilize this testing in pediatric patients admitted to the hospital with minor brain injury. The test would be administered at the time of the hospitalization as well as in the outpatient trauma clinic at the time of routine follow up. The test would allow us to determine if there are neurologic deficits, potentially subclinical, in these brain injured patients and how quickly they recover from their injuries. If successful, the testing will likely be useful in other clinical settings such as the primary care office (e.g. pediatrician), specialty care office (e.g. sports medicine), or emergency room to determine if an injured child requires additional intervention.