New Diagnostic Markers In Dignosis Of Complicated Appendix

Complicated Appendicitis Clinical Trial

Official title:

New Diagnostic Markers In Dignosis Of Complicated Appendix

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06102239
• Other study ID #: Soh-Med-23-09-08Ms
• Status: Recruiting
• Phase: N/A
• Start date: October 1, 2023
• Est. completion date: March 31, 2024

Study information

• Verified date: October 2023
• Source: Sohag University
• Contact: Amr M Amin, Residents
• Phone: 01113486740
• Email: amr_mohamed_post[@]med.sohag.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Most common cause of acute abdomen is acute appendicitis delay dignosis of acute appendicitis lead to complications as perforation this study examined efficacy of hyperbilirubinemia&hyponatremia as indicator of complicated appendicitis

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: March 31, 2024
• Est. primary completion date: March 31, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 10 Years to 40 Years

Eligibility

Inclusion Criteria:

• all patient admitted for acute appendicitis underwent surgery and post operativly confirmed histopathology of acute appendicitis

Exclusion Criteria:

• patient with liver disease Liver transplantation Chronic alcoholism Congental biliary disease Pregnancy Appendicular neoplasm Hemolytic disease Hepatocellular carcinoma

Related Conditions & MeSH terms

• Appendicitis
• Complicated Appendicitis

Intervention

Diagnostic Test:
• Bilirubin level sodium level c reactive protein level
detect level of bilirubin,sodium &c-reactive protein as indicator of complicated appendicitis

Locations

Country	Name	City	State
Egypt	Sohag University hospital	Sohag

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

References & Publications (4)

Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med. 1986 May;15(5):557-64. doi: 10.1016/s0196-0644(86)80993-3. — View Citation

Kanumba ES, Mabula JB, Rambau P, Chalya PL. Modified Alvarado Scoring System as a diagnostic tool for acute appendicitis at Bugando Medical Centre, Mwanza, Tanzania. BMC Surg. 2011 Feb 17;11:4. doi: 10.1186/1471-2482-11-4. — View Citation

Kar S, Behera TK, Jena K, Sahoo AK. Hyperbilirubinemia as a Possible Predictor of Appendiceal Perforation in Acute Appendicitis: A Prospective Study. Cureus. 2022 Feb 2;14(2):e21851. doi: 10.7759/cureus.21851. eCollection 2022 Feb. — View Citation

Virmani S, Prabhu PS, Sundeep PT, Kumar V. Role of laboratory markers in predicting severity of acute appendicitis. Afr J Paediatr Surg. 2018 Jan-Mar;15(1):1-4. doi: 10.4103/ajps.AJPS_47_16. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Level of bilirubin in acute appendicitis		6 months
Primary	Level of sodium in acute appendicitis		6 months
Primary	Level of c-reactive proteins in acute appendicitis		6 months