Complex Regional Pain Syndromes Clinical Trial
Official title:
Sympatholytic Effects of High Thoracic Erector Spinae Plane Block: A Prospective Observational Study on Changes in Optic Nerve Sheath Diameter
The thoracic erector spinae plane (ESP) block is suggested to potentially affect the stellate ganglion, a key component of the sympathetic nervous system, thereby influencing autonomic functions. Changes in optic nerve sheath diameter (ONSD) are used as indicators of intracranial pressure changes. This study aims to investigate the effects of the ESP block on ONSD, providing insights into its impact on the stellate ganglion and enhancing the understanding of the ESP block's safety and efficacy.
The thoracic erector spinae plane (ESP) block is a regional anesthesia technique. This technique involves the injection of local anesthetics into the deep layers of the erector spinae muscles, blocking both somatic and visceral pain pathways. Although various studies have been conducted on the effectiveness of this technique in different clinical situations over the years, further research is needed to understand the precise mechanisms behind its neuroanatomical effects. The stellate ganglion, an important component of the sympathetic nervous system, plays a crucial role in the regulation of several autonomic functions. It has been suggested that the ESP block may affect the stellate ganglion through its injection at the upper thoracic levels. Changes in the optic nerve sheath diameter (ONSD) have been used as an important indicator of intracranial pressure changes. Any potential changes in ONSD following stellate ganglion blockade could help elucidate the effects of the ESP block, thus aiding in the understanding of its safety and potential benefits for analgesia. The aim of this study is to investigate the changes in optic nerve sheath diameter in patients undergoing the thoracic ESP block, which could provide more information on the impact of the ESP block on the stellate ganglion. By doing so, we aim to gain further insights into the potential analgesic effects and safety of the ESP block. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT04066933 -
Forms of Cervical Brachial Syndrome Treated With Plasma Concentrate Enriched for A2M
|
||
| Completed |
NCT04597866 -
Treatment of Complex Regional Pain Syndrome, a Long-term Follow-up
|
||
| Completed |
NCT04060875 -
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
|
||
| Not yet recruiting |
NCT06453447 -
Prednisone for CRPS in Distal Radius Fracture
|
N/A | |
| Terminated |
NCT01954888 -
Impact of the Ultrasound-guided Approach on the Efficiency and Safety of the Stellate Ganglion Block in Chronic Pain
|
N/A | |
| Terminated |
NCT00689585 -
Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS)
|
Phase 2 | |
| Recruiting |
NCT00377468 -
Effect of Delta-9-Tetrahydrocannabinol on the Prevention of Chronic Pain in Patients With Acute CRPS (ETIC-Study)
|
Phase 2 | |
| Recruiting |
NCT05787119 -
Benefit of Augmented Reality Mirror Therapy in Addition to Conventional Management in Complex Regional Pain Syndrome of the Upper Extremity
|
N/A | |
| Recruiting |
NCT05523934 -
Retrospective Analysis of capsaïcin Patch in Complex Regional Pain Syndrome
|
||
| Recruiting |
NCT04732325 -
Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain
|
N/A | |
| Completed |
NCT03174249 -
Exposure Therapy Combined With Cortical Interventions for CRPS-II
|
N/A | |
| Recruiting |
NCT06033456 -
Combining Stellate Ganglion and T2 and T3 Radiofrequency Ablation on Post-mastectomy Complex Regional Pain Syndrome
|
N/A | |
| Recruiting |
NCT04144972 -
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
|
N/A | |
| Completed |
NCT02490436 -
Novel Treatment Option for Neuropathic Pain
|
Phase 2 | |
| Withdrawn |
NCT03316066 -
Comparison of Volumes of Local Anesthetics on the Efficiency and Safety of Stellate Ganglion Block for CRPS of the Arm
|
N/A | |
| Recruiting |
NCT05491499 -
Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
|
||
| Completed |
NCT03291197 -
Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome
|
Phase 4 | |
| Recruiting |
NCT05034835 -
Impact of Compression Garments on Pain in Patients With Complex Regional Pain Syndrome of the Upper Limbs.
|
N/A | |
| Completed |
NCT05696587 -
Physical and Psychological Changes in CRPS Patients Undergoing Multimodal Rehabilitation
|
N/A | |
| Recruiting |
NCT02957240 -
Graded Motor Imagery for Women at Risk for Developing Type I CRPS Following Closed Treatment of Distal Radius Fractures
|
N/A |