Complex Regional Pain Syndromes Clinical Trial
Official title:
Evoked (Magnetic) Cortical Fields for the Comparative Study of Mechanisms Underlying Chronic Non-malignant Pain in Peripheral Nerve Injury (CRPS II) and CRPS I (Chronic Regional Pain Syndrome I)
In order to be able to study the effects of evoked fields with magnetoencephalography (MEG) in two groups of patients, comparison is made with a group of healthy volunteers.
This study is directed at the (central and / or peripheral) mechanisms of pain and the
cortical changes (plasticity) due to chronic non-malignant pain in two groups of patients
and one healthy volunteer group.
The aim of the study is further to evaluate cortical processes by MEG (and fMRI, if
feasible) to quantify and qualify the responses, localise the generators and study the
effects of a pain therapy.
To search for patterns that may result in diagnostic criteria and have an indicative value
for the treatment and the monitoring of the effects.
Finally the study not only intends to support clinical diagnosis but also to provide tools
to monitor treatment and support the choice (algorithm) between SCS and SAN. An algorithm,
facilitating decision making between these two treatments, will be promoted. It should also
provide a clinical decision tool for the use of SAN
;
Observational Model: Cohort, Time Perspective: Prospective
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