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Clinical Trial Summary

The IVUS CHIP trial is a post-marketing strategy study in which patients with complex coronary lesions, undergoing percutaneous coronary intervention (PCI), are treated either with intravascular ultrasound (IVUS) guided PCI or angiographic guided PCI . The IVUS-guided PCI approach is indicated to reduce the frequency of target-lesion failure (cardiac death, target-vessel myocardial infarction, and clinically indicated target-lesion revascularization) in patients with complex coronary lesions undergoing PCI. The objective of this study is to assess the superiority of an IVUS-guided approach versus an angio-guided approach in patients with complex coronary lesions undergoing PCI.

Clinical Trial Description

During percutaneous coronary intervention (PCI) coronary arteries are visualized to guide placing the stent. In this study 2 currently utilized methods of visualizing coronary arteries during PCI are compared: intravascular ultrasound (IVUS) and angiographic guided PCI for patients with complex coronary lesions.The use of IVUS during PCI is suggested to give better results than angiographic guided PCI. The IVUS-CHIP trial is a randomized, controlled, multicenter, international, post-marketing study. A total of 2020 patients, in 7 European countries and approximately 40 hospitals, will be included, randomized in a 1:1 fashion to IVUS-guided PCI versus angio-guided PCI, and followed up for at least 2 years. The IVUS-CHIP is an event-driven study; primary analysis of the data will take place after 169 patients have experienced an event. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT04854070
Study type Interventional
Source ECRI bv
Contact A. van der Wal
Phone +31 6 50127943
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date June 2021
Completion date June 2025

See also
  Status Clinical Trial Phase
Not yet recruiting NCT04837404 - Ultrasound Guided Transfemoral Complex Large-bore PCI Trial N/A
Completed NCT03846752 - Complex Large-bore Radial Percutaneous Coronary Intervention (PCI) Trial N/A