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Complete Heart Block clinical trials

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NCT ID: NCT05666219 Not yet recruiting - Clinical trials for Complete Heart Block

Reversal of Complete Heart Block With Aminophylline in Inferior Wall Myocardial Infarction Patients

Start date: December 19, 2022
Phase: Phase 4
Study type: Interventional

In this study we will evaluate the rate of reversal of complete heart block with aminophylline in atropine resistant patients with inferior wall myocardial infarction (MI)

NCT ID: NCT05541679 Recruiting - Clinical trials for Aortic Valve Stenosis

Comparison of Left Bundle Branch Area Versus Right Ventricular Septal Pacing in Patients With High-degree Conduction Disease After Transcatheter Aortic Valve Replacement (Left Bundle BRAVE)

Start date: December 28, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the superiority of chronic left bundle branch area pacing compared to traditional right ventricular (RV) septal pacing in patients with high-grade conduction disease after transcatheter aortic valve replacement (TAVR). In this investigator initiated, multicenter, prospective, double-blinded, crossover study, chronic left bundle branch area pacing will be compared to chronic right ventricular septal pacing using echocardiographic measures of left ventricular systolic function in patients with a high cumulative ventricular pacing burden after TAVR.

NCT ID: NCT04931693 Completed - Clinical trials for Complete Heart Block

PECs Block for Pacemaker Insertion in Children

Start date: December 20, 2021
Phase: Phase 4
Study type: Interventional

Evaluation of Ultrasound Guided Modified Pectoral Nerves Blocks in Transvenous Subpectoral pacemaker insertion in Children: Randomized Controlled Trial

NCT ID: NCT04245345 Completed - AV Block Clinical Trials

Accelerometer Sensing for Micra AV Study

AccelAV
Start date: June 9, 2020
Phase: N/A
Study type: Interventional

The purpose of the AccelAV Study is to characterize chronic AV synchrony in subjects implanted with MicraTM AV device. This study will be conducted upon market approval of the MicraTM AV Transcatheter Pacing System.

NCT ID: NCT02809131 Completed - Syncope Clinical Trials

Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections.

ENVELOPE
Start date: April 1, 2016
Phase: Phase 3
Study type: Interventional

The number of cardiac implantable electronic devices (CIEDs) implanted each year has grown rapidly over the past two decades. CIED infections, defined as infections involving the generator implant site (pocket) and/or intravascular leads, have become increasingly prevalent, with the rate of growth in infections outpacing that of CIED procedures. The odds of both short term and long term mortality are at least doubled in patients who suffer CIED infections, and long term survival is particularly poor in women. Optimal strategies to prevent CIED infections in high-risk patients are largely unproven. However, recent observational studies of an antibiotic-coated envelope implanted at the time of CIED procedure have shown that this strategy is associated with a low incidence of CIED infections. Other interventions to prevent CIED infections, including the use of antibiotic irrigant used to wash the pocket during implantation and postoperative oral antibiotics, are commonly used but not supported by rigorous controlled studies. The Specific Aim of this study is to test the hypothesis that the use of the antibacterial envelope alone is noninferior to a strategy using the antibacterial envelope and intraoperative antibacterial irrigant and postoperative oral antibiotics for the reduction of cardiac implantable device infections in patients with ≥2 risk factors for infection.

NCT ID: NCT00374608 Completed - Pacemaker Clinical Trials

Exercise in Chronically Paced Children

Start date: January 2007
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the exercise capacity of patients with complete heart block who are chronically being paced from the right ventricle. Also, we hope to correlate the level of uncoordinated contraction with the patients exercise capacity. We will enroll patients with complete heart block as diagnosed by standard electrocardiographic means and now have a permanent pacemaker. All patients we approach for this study will receive an echocardiogram to assess their heart function. As part of the echocardiogram, they will also receive a Tissue Synchronization Imaging (TSI) evaluation to assess the level of uncoordinated contraction they have. The patients will then be subjected to a cardiac exercise stress test which will involve them running on a treadmill until they cannot continue while data is collected regarding their heart's response to exercise. All portions of the study are noninvasive, which means they work from probes and monitors outside the body.