Children With ADHD Symptoms: Comorbid Conditions, Cognitive and Social Performance

Comorbid Conditions Clinical Trial

— NF ADHD  

Official title:

Children With ADHD Symptoms: Comorbid Conditions, Cognitive and Social Performance

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01252446
• Other study ID #: 219.04 REK
• Secondary ID: 219.04(REK)
• Status: Recruiting
• Phase: Phase 1/Phase 2
• First received: November 19, 2010
• Last updated: December 2, 2010
• Start date: September 2008
• Est. completion date: December 2010

Study information

• Verified date: January 2009
• Source: University of Bergen
• Contact: Nezla Duric, M:D:
• Phone: 004790544231
• Email: nezlad[@]gmail.com
• Is FDA regulated: No
• Health authority: Norway:National Committee for Medical and Health Research EthicsNorway: Norwegian Medicines AgencyNorway: Norwegian Social Science Data ServicesNorway: Directorate of Health
• Study type: Observational

Clinical Trial Summary

This article reviews social-demographic variables (SDV) including interpersonal and academic and social performance in families and comorbid conditions(CC) which are the most associated with Attention-Deficit/Hyperactivity Disorder (ADHD)in the sample that has been confirmed diagnosis of ADHD and sample with the same symptoms but not confirmed diagnosis of ADHD.

There are no reports of this kind in the Norwegian population with ADHD.

Description:

ADHD is one of the largest diagnostic groups in psychiatric health care for children and adolescents in Norway. In the guidelines laid out by the central authorities, ADHD is to be prioritized. As can be seen by the attention this topic is given in the media, good diagnostics and treatment for this group are important for society as well as the individuals who suffer from this. Early diagnosis, proper organization and appropriate treatment have a positive effect on the self-esteem and development of the person diagnosed as well as probable socio-economic benefits for society.

ADHD population shows significant pattern in socio-demographic relations and comorbidity according to the population that is referred to community Mental Health Clinic due another types of psychiatric conditions.

In terms of comorbid states ODD and OCD are most associated with ADHD . The study indicates prevalence of ADHD children (74%) who met criteria for ADHD, Combined Type (ADHD-C, both inattention and hyperactivity-impulsivity symptoms) and the existence of generally low IQ measures with mean value of 85 points. In terms of comorbid states generally were found in almost whole ADHD group (93 %) compared to half of the non-ADHD group. Disruptive Behaviour Disorder, Anxiety /Stress related disorder and Encopresis /Enuresis shows significant difference between the groups. Other comorbid conditions show no significant differences. Social dysfunctions were found in four of five children.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 187
• Est. completion date: December 2010
• Est. primary completion date: June 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 6 Years to 17 Years

Eligibility

Inclusion Criteria:

• clinical symptoms related on diagnosis of ADHD

• age from 6-17 years

Exclusion Criteria:

• retardation

• somatic disorder

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

• Comorbid Conditions
• Disease
• Social-demographic Profiles

Locations

Country	Name	City	State
Norway	Child and Adolescent Psychiatry Clinic Helse Fonna Haugesund	Haugesund	Rogaland

Sponsors (2)

Lead Sponsor	Collaborator
University of Bergen	Helse Fonna

Country where clinical trial is conducted

Norway, 

References & Publications (3)

da Silva MA, Louzã MR, Vallada HP. Attention deficit hyperactivity disorder (ADHD) in adults: social-demographic profile from a university hospital ADHD outpatient unit in São Paulo, Brazil. Arq Neuropsiquiatr. 2006 Sep;64(3A):563-7. — View Citation

Jensen PS, Hinshaw SP, Kraemer HC, Lenora N, Newcorn JH, Abikoff HB, March JS, Arnold LE, Cantwell DP, Conners CK, Elliott GR, Greenhill LL, Hechtman L, Hoza B, Pelham WE, Severe JB, Swanson JM, Wells KC, Wigal T, Vitiello B. ADHD comorbidity findings from the MTA study: comparing comorbid subgroups. J Am Acad Child Adolesc Psychiatry. 2001 Feb;40(2):147-58. — View Citation

Pliszka SR. Psychiatric comorbidities in children with attention deficit hyperactivity disorder: implications for management. Paediatr Drugs. 2003;5(11):741-50. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinicians Manuals from Russell A. Barkley as Disruptive Behavior Disorders Rating Scale--Parent Form (Form 4), Disruptive Behavior Disorders Rating Scale--Teacher Form (Form 5) and Clinical Interview--Parent Report Form (Form 6)	The population was selected from a specialized outpatient clinic for Child and Adolescent Mental Health in Norway. ADHD referred children were classified in two groups: ADHD and non-ADHD. The data was obtained by examination of children and adolescent and by personal interviews and questionnaire with parents, teachers, children and adolescent with attention-deficit/hyperactivity disorder (ADHD).	1 year	Yes
Secondary	cognitive performance	Wechsler Intelligence Scale for Children-Revised (WISC-R)	1 year	Yes

External Links

•   MTA study