Community Acquired Pneumonia Clinical Trial
— ECHOPACOfficial title:
Lung Ultrasound for Community-acquired Pneumonia Diagnosis in Emergency Medicine
NCT number | NCT03411824 |
Other study ID # | RC16_0439 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | November 8, 2016 |
Est. completion date | February 8, 2019 |
Verified date | March 2021 |
Source | Nantes University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Community-acquired pneumonia (CAP) is frequently suspected in the Emergency Department (ED). However, usual diagnosis procedure based on clinical features and chest X-Ray has rather bad performances. A recent study on CT performance in suspected CAP found that 58% of classifications were modified by CT when compared with usual procedure. However, extended CT usage in CAP diagnosis is associated with many limitations : availability in a majority of ED, delay, cost and irradiation, in particular In young patients. Lung Ultrasound (LUS) has good performances in CAP diagnosis even when compared with CT. It is a rapid, inexpensive, radiation-free tool available in a majority of ED. It is performed at the patient's bedside with immediate results. The learning curve allows Emergency Physicians (EP) to perform this exam after a relative brief training. The Investigators aim to investigate LUS performances in clinically suspected CAP authentication , and assesses specific diagnostic contributions and impact on antibiotic prescriptions .
Status | Completed |
Enrollment | 90 |
Est. completion date | February 8, 2019 |
Est. primary completion date | February 8, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria : - clinical suspicion of PAC Exclusion Criteria : - documented end-of-life - pregnancy - seriously ill patients |
Country | Name | City | State |
---|---|---|---|
France | La Roche Sur Yon Hospital | La Roche-sur-Yon | |
France | Nantes University Hospital | Nantes | |
France | Poitiers University Hospital | Poitiers | |
France | Saint-Nazaire Hospital | Saint-Nazaire |
Lead Sponsor | Collaborator |
---|---|
Nantes University Hospital |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Frequency of PAC classification modification (definite, probable, possible, excluded) after LUS realization | 95% confidence interval of CAP classification modification frequency before and after LUS realization | Day 0 | |
Secondary | Concordancy of CAP classification diagnosis concordancy ( after LUS) compared to adjudication committee | CAP classification (definite, probable, possible, excluded) and kappa coefficient. | 28 days after enrollment | |
Secondary | Frequency of Antibiotic prescription modification after LUS | 95% confidence interval of antibiotic prescription intention frequency | Day 0 |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02559310 -
Study to Compare Lefamulin to Moxifloxacin (With or Without Linezolid) for the Treatment of Adults With Pneumonia
|
Phase 3 | |
Completed |
NCT01530763 -
Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)
|
Phase 2/Phase 3 | |
Completed |
NCT02517489 -
Community-Acquired Pneumonia : Evaluation of Corticosteroids
|
Phase 3 | |
Not yet recruiting |
NCT01937832 -
A Phase III Study of Faropenem in the Treatment of Adult Community-acquired Bacterial Pneumonia
|
Phase 3 | |
Completed |
NCT02454114 -
HOME FIRST Pilot: a Study of Early Supported Discharge in Patients With Lower Respiratory Tract Infections
|
N/A | |
Completed |
NCT00653172 -
Comparative Study of NXL103 Versus Comparator in Adults With Community Acquired Pneumonia
|
Phase 2 | |
Recruiting |
NCT02139163 -
Epidemiological Study on Community Acquired Pneumonia
|
||
Recruiting |
NCT06210282 -
The Effect of Focused Lung Ultrasonography on Antibiotic Prescribing in General Practice
|
N/A | |
Withdrawn |
NCT02269644 -
A P3 Comparator Trial in Community Acquired Bacterial Pneumonia
|
Phase 3 | |
Recruiting |
NCT01963442 -
Short Duration Treatment of Non-severe Community Acquired Pneumonia
|
Phase 2 | |
Terminated |
NCT00887276 -
Study to Proof the Clinical and Bacteriological Non-inferiority of Ampicillin/Amoxicillin Versus Moxifloxacin in Hospitalized Patients With Non-severe Community-acquired Pneumonia
|
Phase 4 | |
Not yet recruiting |
NCT00390819 -
Epidemiology of Community Acquired Pneumonia in North Israel
|
N/A | |
Completed |
NCT00079885 -
Study Evaluating Tigecycline vs Levofloxacin in Hospitalized With Community-Acquired Pneumonia
|
Phase 3 | |
Not yet recruiting |
NCT04158310 -
Evaluation the Clinical Value of Xiyanping Injection in the Treatment of Community-acquired Pneumonia in Children
|
||
Recruiting |
NCT02552342 -
Corticosteroid Therapy for Severe Community-Acquired Pneumonia
|
Phase 4 | |
Completed |
NCT02922387 -
Smoking Cessation Intervention in Respiratory Inpatients
|
Phase 4 | |
Completed |
NCT00467701 -
Community Acquired Pneumonia in Telemark and Ostfold
|
N/A | |
Completed |
NCT04198571 -
Retrospective Chart Review Study to Assess Characteristics, Treatment Outcomes and Resource Use of Adults Hospitalized for CAP and CSSTi Treated With Zinforo in Multiple Countries
|
||
Completed |
NCT02107001 -
Lung Ultrasound in Pleuritic Chest Pain
|
N/A | |
Completed |
NCT01561885 -
Collaborative Healthcare Professionals Approach in Monitoring of Patient Centered Outcomes Through Pathways
|
N/A |