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Common Cold clinical trials

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NCT ID: NCT05244148 Recruiting - Common Cold Clinical Trials

Two Seawater-based Formulations for Relief of Nasal Congestion in Paediatric Subjects

Start date: November 25, 2021
Phase: N/A
Study type: Interventional

The objective of this clinical trial is to evaluate the tolerance and efficacy of two Stérimar nasal sprays products in children who have nasal congestion due to the common cold.

NCT ID: NCT05159271 Completed - Nasal Congestion Clinical Trials

Efficacy and Safety of Azeol Nasal Spray Versus Placebo in the Treatment of Early Symptoms of Common Cold in Adults

EXSPRAY
Start date: November 22, 2021
Phase: N/A
Study type: Interventional

The main objective is to evaluate the efficacy of Azéol Spray Nasal, taken two times a day, versus placebo on nasal congestion in subject with common cold.

NCT ID: NCT05126407 Completed - Sinusitis Clinical Trials

A Study of Olynth Saline/Ectomed Nasal Drops/Spray Based Upon Previous Usage

Start date: December 17, 2021
Phase:
Study type: Observational

The purpose of this study is to proactively collect customer feedback on the performance aspects and risk factors of Olynth Nasal Saline Drops/Spray and Olynth Ectomed Nasal Spray.

NCT ID: NCT05093478 Recruiting - Clinical trials for Non-allergic Rhinitis

The Prevalence of Local Immunoglobulin E (IgE) Elevation and Its Effect on Intranasal Capsaicin Therapy in the Non-allergic Rhinitis Population

Start date: September 10, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study to determine the therapeutic response of non-allergic rhinitis patients that have been subtyped as non-allergic rhinitis with local IgE elevation or non-allergic rhinopathy to intranasal capsaicin based on visual analog scale and optical rhinometry, to determine the prevalence of non-allergic rhinitis with local IgE elevation in this study's cohort of patients with non-allergic rhinitis identified by rhinitis history and negative skin testing for allergic rhinitis, and to determine the change, if any, in intranasal IgE levels after capsaicin treatment.

NCT ID: NCT05070650 Not yet recruiting - Common Cold Clinical Trials

Efficacy and Safety of the Combination of Acetylcysteine, Paracetamol and Phenylephrine for the Treatment of Common Cold

Start date: September 20, 2024
Phase: Phase 3
Study type: Interventional

Prospective, randomized, multinational, multicenter, double-blind trial in 2 parallel groups of patients

NCT ID: NCT05034328 Completed - Allergy Clinical Trials

Symbiofilm Trial in Allergic Kids (SYMBIOFILM-TAK)

Start date: February 14, 2022
Phase:
Study type: Observational

Healsea® Children is a seawater-based nasal spray supplemented with a natural Symbiofilm® extract (0.02%) isolated from marine bacteria. Symbiofilm has antibiofilm activity against various bacterial pathogens involved in respiratory tract infections.Healsea® Children is indicated in the cleaning and moistening of nasal mucosa during common cold and rhinitis for children above 6 years. This non interventional post-market clinical investigation aimed to confirm the benefit of Healsea® Children in real life setting in children with perennial allergy who are more prone to common cold.

NCT ID: NCT05030324 Completed - Influenza Clinical Trials

A Study to Evaluate the Safety, Tolerability and Efficacy of XC221 in Patients With Uncomplicated Influenza or Other Acute Viral Upper Respiratory Infections

Start date: October 1, 2021
Phase: Phase 2
Study type: Interventional

A multicenter, randomized, double-blind, placebo controlled comparative study to evaluate the safety, tolerability and efficacy of XC221 used at 100 mg daily and at 200 mg daily in patients with uncomplicated influenza or other acute viral upper respiratory infections (URIs) for 5 days of treatment. The primary objective of the study is to evaluate the efficacy of ХС221 at 100 mg and at 200 mg in comparison with placebo regarding its effect on the severity and duration of influenza symptoms and symptoms of other viral URIs (fever and other major signs and symptoms). The secondary objective of the study is to evaluate the safety of ХС221 at 100 mg and at 200 mg in comparison with placebo in the treatment of influenza ad other viral URIs.

NCT ID: NCT05002179 Completed - Clinical trials for Respiratory Tract Infections

Echinaforce Study to Investigate Explorative Pharmacology and Effectiveness to Prevent From Enveloped Virus Infections

Start date: November 20, 2020
Phase: Phase 4
Study type: Interventional

It is a single-center, randomized, open-label, phase IV study for the explorative investigation of the pharmacological mode-of-action of Echinaforce® extract in the form of Echinaforce® Chewable tablets"- Further, it is aimed to evaluate the effectiveness of the study product for the prevention and treatment of respiratory tract infections in generally healthy adults following a real-life setting. The study covers 2x2 + 1 month of prevention in 120 randomized participants following a tight sampling set-up for sensitive detection of viral infections by RT-qPCR analysis of nasal swabs and seroconversion of SARS-CoV2 IgG/IgM in serum samples.

NCT ID: NCT04943575 Completed - Common Cold Clinical Trials

Study to Evaluate the Efficacy of EZC Pak in Adults With Upper Respiratory Infection (URI)

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

A randomized-controlled interventional clinical trial to evaluate the effectiveness of EZC Pak & EZC Pak+D for the treatment of the common cold and/or a URI.

NCT ID: NCT04705584 Not yet recruiting - Clinical trials for Vernal Keratoconjunctivitis

Topical Immuonosuppressant Drugs in Spring Catarrh

Start date: January 2021
Phase: N/A
Study type: Interventional

Spring catarrh is a prevalent type of conjunctival allergic disorder in temperate countries. Topical steroids are the cornerstone management of spring catarrh beside other anti allergic drugs. However, prolonged use of topical steroids especqially in resistant spring catarrh carries risk of ocular side effects as 2nd glaucoma and cataract. We will investigate the safety and efficacy of topical immuonosuppressant in the management of resistant spring catarrh as an alternative to steroid therapy.