Tolerability Clinical Trial
Official title:
Assessment of Novel Respiratory Protective Devices in Healthcare
This VA-based study will obtain feedback from healthcare workers via validated survey instrument on the comfort and tolerability of wearing current models of N95 respirators and novel respirator designs currently in development. There will be 4 novel respirators and 1 commonly used respirator (not locally used) to compare to a locally used respirator, which is familiar to participants. Comparisons will be examined between each of the first 5 models with the locally used control using Dunnett's t-test.
This study aims to compare novel designs to products currently in the marketplace by comparing scores on a survey tool which measures comfort and tolerability of respiratory protective devices. Study participants will be clinical healthcare workers who have experience wearing respiratory protective devices in their workplace. We will enroll up to 400 participants in the study, made up of physicians, nurses, nursing assistants and other healthcare employees who have previously been fit-tested to a N95 respirator. Subjects will be screened to determine eligibility and must pass fit-testing on the respirator he/she is randomized to. Participants will wear the respirator while performing a series of motions that simulate movements made by healthcare workers when performing patient care tasks. There will be no contact with patients during participation. Feedback via validated survey tool will be collected from all study participants on the comfort and tolerability of the respirator worn. ;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04693429 -
Clinical Study for the Evaluation of Safety and Tolerability of PRO-172 Ophthalmic Solution+
|
Phase 1 | |
| Active, not recruiting |
NCT01703871 -
Music During Diagnostic Hysteroscopy
|
N/A | |
| Completed |
NCT01260025 -
Tolerability and Pharmacokinetics of M2ES in the Treatment of Advanced Solid Tumor
|
Phase 1 | |
| Not yet recruiting |
NCT00944268 -
Efficacy and Tolerability Study to Treat Mild and Moderate Anxiety
|
Phase 3 | |
| Completed |
NCT01959685 -
A Dose Escalating Study to Determine the Tolerability and PK of a Single Dose of Androxal
|
Phase 1 | |
| Completed |
NCT01841788 -
Evaluation of Experimental Heat Patch
|
N/A | |
| Completed |
NCT01841801 -
Evaluation of Experimental and Commercial Air-Activated, Adhesive Backed Heat Patches
|
N/A | |
| Completed |
NCT01158755 -
Intensified Treatment Regimens for TB Meningitis: PK, PD and Tolerability Study
|
Phase 2 | |
| Completed |
NCT05633147 -
Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam
|
Phase 1 | |
| Completed |
NCT01981928 -
A Clinical Trial to Investigate Safety and Tolerability of ASP7962 in Healthy Humans
|
Phase 1 | |
| Completed |
NCT01954589 -
Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206
|
Phase 1 | |
| Completed |
NCT01023282 -
Safety and Tolerability Study Evaluating ACR325 in Parkinson's Disease Patients
|
Phase 1 | |
| Completed |
NCT02512575 -
A Single Ascending Dose Study To Assess The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of AZD9567.
|
Phase 1 | |
| Recruiting |
NCT05142592 -
IPG7236 in Patients With Advanced Solid Tumors
|
Phase 1 | |
| Completed |
NCT05044949 -
Study Evaluating the Safety and Tolerability of a Probioitc
|
N/A | |
| Completed |
NCT05795192 -
SB17170 Phase1 Trial in Healthy Volunteer
|
Phase 1 | |
| Completed |
NCT01121302 -
Study to Investigate Single Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects
|
Phase 1 | |
| Completed |
NCT05847218 -
Phase 1 Clinical Trial of RHN-001 in Healthy Adult Volunteers
|
Phase 1 | |
| Terminated |
NCT03503968 -
TCR Modified T Cells MDG1011 in High Risk Myeloid and Lymphoid Neoplasms
|
Phase 1/Phase 2 | |
| Completed |
NCT02107885 -
Single Ascending Dose Study Using DS-1971 to Assess Safety, Tolerability, and Pharmacokinetics in Healthy Participants.
|
Phase 1 |