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Combined Immunodeficiencies clinical trials

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NCT ID: NCT02737384 Terminated - Clinical trials for Combined Immunodeficiencies

Hematopoietic Stem Cells Transplantation in Children With Combined Immunodeficiency (CID)

CD45RA
Start date: June 14, 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate selective depletion of naïve CD45RA+ T cells from allogenic peripheral blood stem cell graft in children transplanted for combined immune deficiency. The aims of this procedure are to prevent graft versus host disease (GVHD) while preserving anti-infectious response from donor memory T lymphocytes.